购物车
- 全部删除
您的购物车当前为空
Anti-Phospho-EGFR (Tyr1092) Antibody (9I899)
还可以产品编号 TMAH-00891
别名 PIG61, Phospho-EGFR (Y1092), NISBD2, mENA, LEGFR, HER1, ERBB1, ErbB, EGFR, EC 2.7.10.1, EC 2.7.10
Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) 是一种抗体，靶向 Phospho-EGFR (Tyr1092)。Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) 可用于 ELISA, WB。
Anti-Phospho-EGFR (Tyr1092) Antibody (9I899)
Anti-Phospho-EGFR (Tyr1092) Antibody (9I899)
还可以产品编号 TMAH-00891 别名 PIG61, Phospho-EGFR (Y1092), NISBD2, mENA, LEGFR, HER1, ERBB1, ErbB, EGFR, EC 2.7.10.1, EC 2.7.10
Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) 是一种抗体，靶向 Phospho-EGFR (Tyr1092)。Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) 可用于 ELISA, WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,305 | 5日内发货 | |
| 100 μL | ¥ 2,195 | 5日内发货 |
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) is an antibody targeting Phospho-EGFR (Tyr1092). Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) can be used in ELISA, WB. |
| 别名 | PIG61, Phospho-EGFR (Y1092), NISBD2, mENA, LEGFR, HER1, ERBB1, ErbB, EGFR, EC 2.7.10.1, EC 2.7.10 |
| Ig Type | Rabbit IgG |
| 克隆号 | 9I899 |
| 交叉反应 | Human |
| 验证活性 | Western Blot -Positive WB detected in A549 whole cell lysate,Hela whole cell lysate(treated with Pervanadate or EGF) -All lanes Phospho-EGFR antibody at 1.35μg/ml -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 170 KDa -Observed band size: 170 KDa |
| 应用 | ELISA, WB |
| 推荐剂量 | WB:1:500-1:5000. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Nucleus membrane; Single-pass type I membrane protein. Endosome. Endosome membrane. Nucleus.; [Isoform 2]: Secreted. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. Positively regulates cell migration via interaction with CCDC88A/GIV which retains EGFR at the cell membrane following ligand stimulation, promoting EGFR signaling which triggers cell migration. Plays a role in enhancing learning and memory performance. Isoform 2 may act as an antagonist of EGF action. (Microbial infection) Acts as a receptor for hepatitis C virus (HCV) in hepatocytes and facilitates its cell entry. Mediates HCV entry by promoting the formation of the CD81-CLDN1 receptor complexes that are essential for HCV entry and by enhancing membrane fusion of cells expressing HCV envelope glycoproteins. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human Phospho-EGFR (Y1092) |
| 抗原种属 | Human |
| 基因ID | 1956 |
| Uniprot ID | |
| 研究领域 | Signal Transduction |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) | purchase Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) | Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) cost | order Anti-Phospho-EGFR (Tyr1092) Antibody (9I899)
嗨！有任何问题？点我咨询
评论内容