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Anti-Gli3 Antibody (3M730) 是一种 Rabbit 抗体,靶向 Gli3。Anti-Gli3 Antibody (3M730) 可用于 WB,ICC。
Anti-Gli3 Antibody (3M730) 是一种 Rabbit 抗体,靶向 Gli3。Anti-Gli3 Antibody (3M730) 可用于 WB,ICC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,485 | 5日内发货 |
产品描述 | Anti-Gli3 Antibody (3M730) is a Rabbit antibody targeting Gli3. Anti-Gli3 Antibody (3M730) can be used in WB,ICC. |
别名 | Zinc finger protein GLI3, Zinc finger protein GLI 3, Transcriptional repressor GLI3R, Transcriptional activator GLI3, PPDIV, PPD IV, PHS, PAPB, PAPA1, PAPA 1, PAPA, PAP A, Oncogene GLI3, Glioma associated oncogene family zinc finger 3, GLI3FL, GLI3-83, GLI3-190, GLI3_HUMAN, GLI3 full length protein, GLI3 form of 83 kDa, GLI3 form of 190 kDa, GLI3 C-terminally truncated form, GLI Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome), GLI Kruppel family member GLI3, GLI Kruppel family member GLI 3, GLI family zinc finger 3, GLI 3, Gli 3, GCPS, DNA binding protein, ACLS |
Ig Type | IgG |
克隆号 | 3M730 |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of Gli3 on PC-3M cell lysate using anti-Gli3 antibody at 1/1,000 dilution. |
应用 | |
推荐剂量 | WB: 1:500-2000; ICC: 1:50-100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr??ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. GLI-3 (GLI family zinc finger 3), also known as GLI3FL (GLI3 full length protein), PHS, ACLS, GCPS, PAPA, PAPB, PAPA1 or PPDIV, is a 1,580 amino acid nuclear and cytoplasmic protein that acts as both a transcriptional activator and a repressor of the Sonic hedgehog (Shh) pathway. A member of the GLI C2H2-type zinc-finger protein family, GLI-3 is encoded by a gene that maps to human chromosome 7p14.1. Defects in the GLI-3 gene are the cause of a disorder known as Greig cephalo-poly-syndactyly syndrome (GCPS), which affects limb and craniofacial development. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein: human Gli3 aa 1300-1600 |
抗原种属 | human |
Uniprot ID |
分子量 | Theoretical: 190 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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