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Anti-LIMPII/SR-B2 Antibody (7J773)

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产品编号 TMAY-03063
别名 SR-BII, scavenger receptor class B, member 2, LIMPII, LIMP-2, LGP85, HLGP85, EPM4, CD36L2, AMRF

Anti-LIMPII/SR-B2 Antibody (7J773) 是一种 Rabbit 抗体,靶向 LIMPII/SR-B2。Anti-LIMPII/SR-B2 Antibody (7J773) 可用于 IHC-P,ICC/IF。

Anti-LIMPII/SR-B2 Antibody (7J773)

Anti-LIMPII/SR-B2 Antibody (7J773)

Rating icon 还可以
产品编号 TMAY-03063 别名 SR-BII, scavenger receptor class B, member 2, LIMPII, LIMP-2, LGP85, HLGP85, EPM4, CD36L2, AMRF

Anti-LIMPII/SR-B2 Antibody (7J773) 是一种 Rabbit 抗体,靶向 LIMPII/SR-B2。Anti-LIMPII/SR-B2 Antibody (7J773) 可用于 IHC-P,ICC/IF。

规格价格库存数量
100 μL
¥ 2,294
5日内发货
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产品介绍

生物活性
产品描述
Anti-LIMPII/SR-B2 Antibody (7J773) is a Rabbit antibody targeting LIMPII/SR-B2. Anti-LIMPII/SR-B2 Antibody (7J773) can be used in IHC-P,ICC/IF.
别名SR-BII, scavenger receptor class B, member 2, LIMPII, LIMP-2, LGP85, HLGP85, EPM4, CD36L2, AMRF
Ig Type
Monoclonal Rabbit IgG
克隆号
7J773
交叉反应
Mouse
验证活性
1. Immunochemical staining of mouse SCARB2 in mouse kidney with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).

2. Immunochemical staining of mouse SCARB2 in mouse brain with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).

3. Immunofluorescence staining of mouse SCARB2 in mouse splenocytes. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with rabbit anti-mouse SCARB2 monoclonal antibody (1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue).
应用
IHC-P,ICC/IF
推荐剂量
IHC-P: 1:100-1:500; ICC-IF: 1:20-1:100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse LIMP-2 / SCARB2 / CD36L2 (rM LIMP-2 / SCARB2 / CD36L2; TMPY-01434; NP_031670.1; Met1-Thr432).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Lysosomal Integral Membrane Protein II (LIMPII), also known as SCARB2, LPG85, and CD36L2, is a type I II multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. This protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. LIMPII is identified as a receptor for EV71 (human enterovirus species A, Enterovirus 71) and CVA16 (coxsackievirus A16) which are most frequently associated with hand, foot and mouth disease (HFMD). Expression of human LIMPII enables normally unsusceptible cell lines to support the viruses’ propagation and develop cytopathic effects. In addition, LIMPII also has been shown to bind thrombospondin-1, and may contribute to the pro-adhesive changes of activated platelets during coagulation, and inflammation. Deficiency of the protein in mice impairs cell membrane transport processes and causes pelvic junction obstruction, deafness, and peripheral neuropathy.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
APC/FITC/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Mouse LIMP-2 / SCARB2 / CD36L2 protein (TMPY-01434)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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