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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CD11b Antibody (3C556)

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货号 TMAB-03828

Anti-CD11b Antibody (3C556) 是一种 Rabbit 抗体，靶向 CD11b。Anti-CD11b Antibody (3C556) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-CD11b Antibody (3C556)

Anti-CD11b Antibody (3C556)

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Rating icon 还可以
货号 TMAB-03828

Anti-CD11b Antibody (3C556) 是一种 Rabbit 抗体，靶向 CD11b。Anti-CD11b Antibody (3C556) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD11b Antibody (3C556) is a Rabbit antibody targeting CD11b. Anti-CD11b Antibody (3C556) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
3C556
反应种属
Human
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:200-1000; IHC-Fr: 1:200-1000; IF: 1:200-1000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Membrane.
组织特异性Predominantly expressed in monocytes and granulocytes.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
抗原信息
免疫原
Recombinant Protein: Human ITGAM
抗原种属
Human
基因名称
ITGAM
基因ID
3684
蛋白名称
Integrin alpha-M
Uniprot ID
P11215
功能
Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
化学信息
分子量Theoretical: 170 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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