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Anti-Her2/ERBB2 Antibody-APC (6Y940)

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产品编号 TMAY-00034A

Anti-Her2/ERBB2 Antibody-APC (6Y940) 是一种 APC-conjugated Mouse 抗体,靶向 Her2/ERBB2。Anti-Her2/ERBB2 Antibody-APC (6Y940) 可用于 FCM。

Anti-Her2/ERBB2 Antibody-APC (6Y940)

Anti-Her2/ERBB2 Antibody-APC (6Y940)

Rating icon 还可以
产品编号 TMAY-00034A

Anti-Her2/ERBB2 Antibody-APC (6Y940) 是一种 APC-conjugated Mouse 抗体,靶向 Her2/ERBB2。Anti-Her2/ERBB2 Antibody-APC (6Y940) 可用于 FCM。

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产品介绍

生物活性
产品描述
Anti-Her2/ERBB2 Antibody-APC (6Y940) is a APC-conjugated Mouse antibody targeting Her2/ERBB2. Anti-Her2/ERBB2 Antibody-APC (6Y940) can be used in FCM.
Ig Type
Monoclonal Mouse IgG1
克隆号
6Y940
交叉反应
Human
验证活性
Flow cytometric analysis of anti-Human ErbB2 on SKBR3 cells.
应用
FCM
推荐剂量
2 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ErbB2 / HER2 / CD340 (rh ErbB2 / HER2 / CD340; TMPY-01137; NP_004439.2; Met 1-Thr 652) and conjugated with APC under optimum conditions, the unreacted APC was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.03%ProClin300
研究背景Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
APC
其他可选修饰符
Unconjugated/FITC/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Human ErbB2 protein (TMPY-01137)
抗原种属
Human
研究领域
Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs)
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
运输方式Shipping with blue ice.

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