4-Chloro-2'-bromoacetophenone

Name: 4-Chloro-2'-bromoacetophenone
Brand: TargetMol
SKU: T8908
Price: 113 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.41%

货号 T8908Cas号 536-38-9

别名 alpha-溴代-4-氯苯乙酮

4-Chloro-2'-bromoacetophenone 抗糖原合酶激酶 3 (GSK-3beta)。

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4-Chloro-2'-bromoacetophenone

一键复制产品信息

很棒

纯度: 99.41%

货号 T8908 别名 alpha-溴代-4-氯苯乙酮Cas号 536-38-9

4-Chloro-2'-bromoacetophenone 抗糖原合酶激酶 3 (GSK-3beta)。

规格	价格	库存
2 mg	¥ 113	现货
5 mg	¥ 172	现货
10 mg	¥ 257	现货
25 mg	¥ 441	现货
50 mg	¥ 653	现货
100 mg	¥ 990	现货
200 mg	¥ 1,480	现货

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纯度: 99.41%

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COA HNMR LCMS 产品操作手册

产品介绍

4-Chloro-2'-bromoacetophenone AI Summary

4-Chloro-2'-bromoacetophenone exhibits inhibitory activity against glycogen synthase kinase-3 beta (GSK-3beta) with an IC50 value of 1000.0 nM, measured using GS-1 as a substrate in a radiometric assay with [gamma-32P]ATP after 20 minutes. Additionally, 4-Chloro-2'-bromoacetophenone shows inhibitory activity against protein kinase A (PKA) with an IC50 value greater than 100000.0 nM. It also acts as an inhibitor of Polymerase Iota (IC50 = 89125.1 nM), TGF-b (IC50 = 22387.2 nM), and human tyrosyl-DNA phosphodiesterase 1 both in the absence (IC50 = 35481.3 nM) and presence of CPT (IC50 = 25118.9 nM)..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	4-Chloro-2'-bromoacetophenone against glycogen synthase kinase-3 (GSK-3beta).
别名	alpha-溴代-4-氯苯乙酮

化学信息

分子量	233.49
分子式	C₈H₆BrClO
CAS No.	536-38-9
Smiles	ClC1=CC=C(C=C1)C(=O)CBr
密度	1.598g/cm3

储存&溶解度

存储

store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 45 mg/mL (192.73 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.2828 mL	21.4142 mL	42.8284 mL	214.1419 mL
5 mM	0.8566 mL	4.2828 mL	8.5657 mL	42.8284 mL
10 mM	0.4283 mL	2.1414 mL	4.2828 mL	21.4142 mL
20 mM	0.2141 mL	1.0707 mL	2.1414 mL	10.7071 mL
50 mM	0.0857 mL	0.4283 mL	0.8566 mL	4.2828 mL
100 mM	0.0428 mL	0.2141 mL	0.4283 mL	2.1414 mL