规格

价格

库存

数量

1 mg

¥ 179

现货

5 mg

¥ 413

现货

10 mg

¥ 696

现货

25 mg

¥ 1,300

现货

50 mg

¥ 2,080

现货

100 mg

¥ 2,970

现货

200 mg

¥ 4,110

现货

1 mL x 10 mM (in DMSO)

¥ 353

现货

生物活性

产品描述	CPDA is a new potent inhibitor of SH2 domain-containing inositol phosphatase 2 (SHIP2).
体外活性	CPDA enhances insulin signaling. CPDA was found to enhance in vitro insulin signaling through the Akt pathway more efficiently than the previously reported SHIP2 inhibitor AS1949490, and ameliorated abnormal glucose metabolism in diabetic (db/db) mice.
体内活性	CPDA greatly improves abnormal glucose metabolism in diabetic animals. In db/db mice, CPDA improves abnormal glucose metabolism.

化学信息

分子量	388.8
分子式	C₂₀H₁₅ClF₂N₂O₂
CAS No.	1415834-63-7
Smiles	Fc1cccc(F)c1CC(=O)Nc1cc(OCc2ccc(Cl)cc2)ccn1
密度	1.381 g/cm3 (Predicted)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 50 mg/mL (128.6 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.14 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5720 mL	12.8601 mL	25.7202 mL	128.6008 mL
5 mM	0.5144 mL	2.5720 mL	5.1440 mL	25.7202 mL
10 mM	0.2572 mL	1.2860 mL	2.5720 mL	12.8601 mL
20 mM	0.1286 mL	0.6430 mL	1.2860 mL	6.4300 mL
50 mM	0.0514 mL	0.2572 mL	0.5144 mL	2.5720 mL
100 mM	0.0257 mL	0.1286 mL	0.2572 mL	1.2860 mL

CPDA

CPDA

产品介绍

计算器

体内实验配液计算器

剂量转换

引用文献

关键词

CPDA

CPDA

CPDA 相关产品

产品介绍

计算器

体内实验配液计算器

剂量转换

引用文献

关键词