购物车
- 全部删除
您的购物车当前为空
Anti-Apolipoprotein H/APOH Antibody (8K845)
还可以产品编号 TMAY-01772
Anti-Apolipoprotein H/APOH Antibody (8K845) 是一种 Mouse 抗体，靶向 Apolipoprotein H/APOH。Anti-Apolipoprotein H/APOH Antibody (8K845) 可用于 ELISA(Det)。
Anti-Apolipoprotein H/APOH Antibody (8K845)
Anti-Apolipoprotein H/APOH Antibody (8K845)
还可以产品编号 TMAY-01772
Anti-Apolipoprotein H/APOH Antibody (8K845) 是一种 Mouse 抗体，靶向 Apolipoprotein H/APOH。Anti-Apolipoprotein H/APOH Antibody (8K845) 可用于 ELISA(Det)。
产品信息正在更新中，如果您想购买，请点击大包装&定制按钮.
大包装 & 定制
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Apolipoprotein H/APOH Antibody (8K845) is a Mouse antibody targeting Apolipoprotein H/APOH. Anti-Apolipoprotein H/APOH Antibody (8K845) can be used in ELISA(Det). |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 8K845 |
| 交叉反应 | Human |
| 应用 | ELISA(Det) |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Apolipoprotein H (rh Apolipoprotein H; TMPY-01278; NP_000033.2; Met1-Cys345). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Apolipoprotein H (APOH), also known as Beta-2-glycoprotein 1, Activated protein C-binding protein, B2GPI, and B2G1, is a glycoprotein synthesized by liver cells and it is present in the blood associated with plasma lipoproteins. It is an essential cofactor for the binding of certain antiphospholipid antibodies (APA) to anionic phospholipid. APOH binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. APOH may prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. APOH appears to completely inhibit serotonin release by the platelets and prevents subsequent waves of the ADP-induced aggregation. The activity of APOH appears to involve the binding of agglutenating, negatively charged compounds, and inhibits agglutenation by the contact activation of the intrinsic blood coagulation pathway. APOH causes a reduction of the prothrombinase binding sites on platelets and reduces the activation caused by collagen when thrombin is present at physiological serum concentrations of APOH suggesting a regulatory role of APOH in coagulation. APOH plasma concentrations are strongly associated to metabolic syndrome alterations and vascular disease in type 2 diabetic and could be considered as a clinical marker of cardiovascular risk. APOH is found on several classes of lipoproteins, and is involved in the activation of lipoprotein lipase in lipid metabolism. This single-chain glycoprotein also has been implicated in several physiologic pathways including coagulation and the production of hypertension, which are related to the pathogenesis of primary cerebral hemorrhage (PICH). |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Apolipoprotein H Protein (TMPY-01278) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-Apolipoprotein H/APOH Antibody (8K845) | purchase Anti-Apolipoprotein H/APOH Antibody (8K845) | Anti-Apolipoprotein H/APOH Antibody (8K845) cost | order Anti-Apolipoprotein H/APOH Antibody (8K845)
嗨！有任何问题？点我咨询
评论内容