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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-FBXL21 Polyclonal Antibody

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货号 TMAB-05924

Anti-FBXL21 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FBXL21。Anti-FBXL21 Polyclonal Antibody 可用于 WB。

Anti-FBXL21 Polyclonal Antibody

Anti-FBXL21 Polyclonal Antibody

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货号 TMAB-05924

Anti-FBXL21 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FBXL21。Anti-FBXL21 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-FBXL21 Polyclonal Antibody is a Rabbit antibody targeting FBXL21. Anti-FBXL21 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Cow,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景FBL3B is a 434 amino acid protein encoded by the human gene FBXL21. FBL3B contains one 40 amino acid F-box region, making it a member of the F-box family. FBL3B also contains three LRR (leucine-rich) repeats. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. F-box proteins are members of a large family that regulates cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-a and b-catenin, for degradation by the proteasome after ubiquitination. FBL3B is a substrate-recognition component of the SCF complex that interacts with Skp1 p19 and CUL-1. FBL3B is also associated with expression and regulation of circadian and cryptochrome proteins.
抗原信息
免疫原
KLH conjugated synthetic peptide: human FBXL21/FBL3B
抗原种属
Human
基因名称
FBXL21P
基因ID
26223
蛋白名称
Putative F-box/LRR-repeat protein 21
Uniprot ID
Q9UKT6
功能
Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian pacemaker function. The SCF(FBXL21) complex acts by mediating ubiquitination and subsequent degradation of CRY1. Probable clock-controlled protein that plays a specific role in suprachiasmatic nucleus, SCN and pacemaker function.
化学信息
分子量Theoretical: 49 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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