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Anti-CXCL1 Antibody (2Q668)

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Anti-CXCL1 Antibody (2Q668)
产品编号 TMAY-01275
别名 SCYB1, P450c21B, NAP-3, MGSA-a, MGSA, GROa, GRO1, CYP21B, CYP21, CPS1, chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, α), chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha), CAH1, CA21H

Anti-CXCL1 Antibody (2Q668) 是一种 Rabbit 抗体,靶向 CXCL1。Anti-CXCL1 Antibody (2Q668) 可用于 ELISA。

Anti-CXCL1 Antibody (2Q668)
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Anti-CXCL1 Antibody (2Q668)

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Anti-CXCL1 Antibody (2Q668)
产品编号 TMAY-01275 别名 SCYB1, P450c21B, NAP-3, MGSA-a, MGSA, GROa, GRO1, CYP21B, CYP21, CPS1, chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, α), chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha), CAH1, CA21H

Anti-CXCL1 Antibody (2Q668) 是一种 Rabbit 抗体,靶向 CXCL1。Anti-CXCL1 Antibody (2Q668) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-CXCL1 Antibody (2Q668) is a Rabbit antibody targeting CXCL1. Anti-CXCL1 Antibody (2Q668) can be used in ELISA.
别名SCYB1, P450c21B, NAP-3, MGSA-a, MGSA, GROa, GRO1, CYP21B, CYP21, CPS1, chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, α), chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha), CAH1, CA21H
Ig Type
Rabbit IgG
克隆号
2Q668
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human CXCL1 (rh CXCL1; TMPY-02868; P09341-1; Ala35-Asn107).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景The Chemokine (C-X-C motif) Ligand 1, CXCL1, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-a). CXCL1 already known to be important in osteoarthritis (OA), as a novel target gene of transcription factor AP-2? in chondrocytes and support the important role of AP-2? in cartilage. CXCL1 is a potent neutrophil chemoattractant with recognized roles in angiogenesis and inflammation. CXCL1 is a novel immediate PTH/PTHrP-responsive gene. CXCL1 may act as a chemoattractant for osteoclast precursors. CXCL1 may also have important pro-nociceptive effects via its direct actions on sensory neurons, and may induce long-term changes that involve protein synthesis. CXCL1 plays a critical nonredundant role in the development of experimental Lyme arthritis and carditis via CXCR2-mediated recruitment of neutrophils into the site of infection. CXCL1 functions through CXCR2 to transactivate the EGFR by proteolytic cleavage of HB-EGF, leading to activation of MAPK signalling and increased proliferation of epithelial ovarian cancer (EOC) cells. It might limit tumor growth by reinforcing senescence early in tumorigenesis. Thus, CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation, wound healing, and tumorigenesis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human CXCL1 Protein (TMPY-02868)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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