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CPA inhibitor

Name: CPA inhibitor
Brand: TargetMol
SKU: T10876
Price: 413 CNY
Availability: InStock
Rating: 5 (10 reviews)

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纯度: 99.94%

货号 T10876Cas号 223532-02-3

别名 Carboxypeptidase inhibitor

CPA inhibitor (Carboxypeptidase inhibitor) 是一种有效的羧肽酶 A (CPA) 抑制剂，Ki 值为 0.32 μM。

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CPA inhibitor

一键复制产品信息

很棒

纯度: 99.94%

货号 T10876 别名 Carboxypeptidase inhibitorCas号 223532-02-3

CPA inhibitor (Carboxypeptidase inhibitor) 是一种有效的羧肽酶 A (CPA) 抑制剂，Ki 值为 0.32 μM。

规格	价格	库存
1 mg	¥ 413	现货
5 mg	¥ 987	现货
10 mg	¥ 1,450	现货
25 mg	¥ 2,510	现货
50 mg	¥ 3,670	现货
1 mL x 10 mM (in DMSO)	¥ 703	现货

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产品介绍

CPA inhibitor AI Summary

CPA inhibitor inhibits carboxypeptidase A (CPA) with a Ki value of 320.0 nM. It exhibits antiviral activity against SARS-CoV-2, inhibiting cytotoxicity in Caco-2 and VERO-6 cells at a concentration of 10 µM after 48 hours, although the inhibition percentages range from -10.7% to -0.04%. Additionally, CPA inhibitor shows inhibitory activity against the SARS-CoV-2 3CL-Pro protease, with inhibition percentages of 8.99% and 19.17% at 20 µM, indicating potential bioactivity in inhibiting the viral replication enzyme. Moreover, the compound exhibits inhibitory effects against human HDAC6 in enzymatic assays, showing inhibition levels of -13.12% and -17.17% with commercial and custom peptide substrates, respectively, suggesting a potential for modulating HDAC6 activity..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	CPA inhibitor (Carboxypeptidase inhibitor) is a potent carboxypeptidase A (CPA) inhibitor with a Ki of 0.32 μM.
靶点活性	CPA:0.32 μM (Ki)
别名	Carboxypeptidase inhibitor

化学信息

分子量	313.35
分子式	C₁₈H₁₉NO₄
CAS No.	223532-02-3
Smiles	ON(CC(Cc1ccccc1)C(O)=O)C(=O)Cc1ccccc1
密度	1.274
颜色	White
物理性状	Solid

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 90 mg/mL (287.22 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (10.53 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1913 mL	15.9566 mL	31.9132 mL	159.5660 mL
5 mM	0.6383 mL	3.1913 mL	6.3826 mL	31.9132 mL
10 mM	0.3191 mL	1.5957 mL	3.1913 mL	15.9566 mL
20 mM	0.1596 mL	0.7978 mL	1.5957 mL	7.9783 mL
50 mM	0.0638 mL	0.3191 mL	0.6383 mL	3.1913 mL
100 mM	0.0319 mL	0.1596 mL	0.3191 mL	1.5957 mL