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Anti-LOX-1 Antibody (4V907)
还可以产品编号 TMAY-00993
Anti-LOX-1 Antibody (4V907) 是一种 Mouse 抗体，靶向 LOX-1。Anti-LOX-1 Antibody (4V907) 可用于 ELISA。
Anti-LOX-1 Antibody (4V907)
Anti-LOX-1 Antibody (4V907)
还可以产品编号 TMAY-00993
Anti-LOX-1 Antibody (4V907) 是一种 Mouse 抗体，靶向 LOX-1。Anti-LOX-1 Antibody (4V907) 可用于 ELISA。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-LOX-1 Antibody (4V907) is a Mouse antibody targeting LOX-1. Anti-LOX-1 Antibody (4V907) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG2a |
| 克隆号 | 4V907 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human OLR1/LOX1 (rh OLR1/LOX1; TMPY-02490; P78380; Ser61-Gln273). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1 or OLR1), also known as lectin-type oxidized LDL receptor 1 (LOX1), is a receptor protein that belongs to the C-type lectin superfamily. LOX1 is a multi-ligand receptor originally identified as the endothelial oxidized LDL receptor. OLR1 / LOX1 was isolated from an aortic endothelial cell, and recently it has been discovered in macrophages and vascular smooth muscle cells in artery vessels. The expression of LOX1 is induced by inflammatory stimuli and oxidative stimuli. This protein binds, internalizes, and degrades oxidized low-density lipoprotein. LOX1 may play an important role in the progression of vulnerable carotid plaque and might regulate vulnerable plaque formation in cooperation with MMPs and TIMP-2. In clinical, LOX1 is thought to be involved in the development of atherosclerotic lesions. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human OLR1/LOX1 Protein (TMPY-02490) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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