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Anti-B7-1 Antibody (3V341) 是一种 Rabbit 抗体,靶向 B7-1。Anti-B7-1 Antibody (3V341) 可用于 ELISA。
Anti-B7-1 Antibody (3V341) 是一种 Rabbit 抗体,靶向 B7-1。Anti-B7-1 Antibody (3V341) 可用于 ELISA。
产品描述 | Anti-B7-1 Antibody (3V341) is a Rabbit antibody targeting B7-1. Anti-B7-1 Antibody (3V341) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 3V341 |
交叉反应 | Cynomolgus, Rhesus |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Cynomolgus / Rhesus CD80 / B7-1 ( TMPY-04349; ; Met1-Asn242). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | The B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. As costimulatory ligands, B7-1 which exists predominantly as dimer and the related protein B7-2, interact with the costimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus constitute one of the dominant pathways that regulate T cell activation and tolerance, cytokine production, and the generation of CTL. The B7/CD28/CTLA4 pathway has the ability to both positively and negatively regulate immune responses. CD80 is thus regarded as promising therapeutic targets for autoimmune diseases and various carcinomas.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
偶联 | Unconjugated |
免疫原 | Recombinant Cynomolgus / Rhesus CD80 / B7-1 Protein (TMPY-04349) |
抗原种属 | Cynomolgus, Rhesus |
研究领域 | Cancer Drug Targets |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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