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Anti-Phospho-LIMK2 (Ser283) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-LIMK2 (Ser283)。Anti-Phospho-LIMK2 (Ser283) Polyclonal Antibody 可用于 WB,IHC-P,IF(paraffin section),ELISA。
Anti-Phospho-LIMK2 (Ser283) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-LIMK2 (Ser283)。Anti-Phospho-LIMK2 (Ser283) Polyclonal Antibody 可用于 WB,IHC-P,IF(paraffin section),ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,245 | 5日内发货 |
产品描述 | Anti-Phospho-LIMK2 (Ser283) Polyclonal Antibody is a Rabbit antibody targeting Phospho-LIMK2 (Ser283). Anti-Phospho-LIMK2 (Ser283) Polyclonal Antibody can be used in WB,IHC-P,IF(paraffin section),ELISA. |
别名 | p-LIMK2 (Ser283), p-LIMK2 (S283), LIMK2 (p-Ser283), LIMK2 (p-S283) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat,Monkey |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-300; ELISA: 1:5000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
性状 | Liquid |
缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
研究背景 | LIM domain kinase 2(LIMK2) Homo sapiens There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. The protein encoded by this gene is phosphorylated and activated by ROCK, a downstream effector of Rho, and the encoded protein, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton. At least three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | A synthesized phosphopeptide: human LIMK2 around the phosphorylation site of Ser283. AA range:249-298 |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 72 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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