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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-GIPC1 Polyclonal Antibody

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货号 TMAB-06483

Anti-GIPC1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GIPC1。Anti-GIPC1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-GIPC1 Polyclonal Antibody

Anti-GIPC1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-06483

Anti-GIPC1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GIPC1。Anti-GIPC1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-GIPC1 Polyclonal Antibody is a Rabbit antibody targeting GIPC1. Anti-GIPC1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Cow,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell Membrane, peripheral membrane protein and Cytoplasmic.
组织特异性Widely expressed.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景GIPC, for GAIP interacting protein at the C terminus (also designated SEMCAP-1 or synectin), is a PDZ domain containing protein that interacts with RGS-GAIP, a GTPase-activating protein (GAP) for G(a i) subunits. GIPC was also identified as TIP-2, a protein that interacts with the viral oncoprotein TAX, which transactivates viral and cellular promoters through interactions with various transcription factors. PDZ domain-containing proteins are primarily localized to cell-cell junctions in epithelial cells and neurons where they coordinate the assembly of multiprotein complexes. GIPC specifically localizes to clusters of vesicles near the plasma membrane and participates in G protein-coupled signaling pathway involved in regulating clathrin-coated vesicular trafficking. GIPC also associates with membrane bound semaphorin F (M-SemF), which is involved in neuronal axon growth, and it appears to regulate the subcellular distribution of M-SemF in the brain.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GIPC1
抗原种属
Human
基因名称
GIPC1
基因ID
10755
蛋白名称
PDZ domain-containing protein GIPC1
Uniprot ID
O14908
功能
GIPC1 is a hydrophilic protein that contains 333 amino acids, including multiple phosphorylation sites and an 80 to 100 amino acid PDZ domain. PDZ domain-containing proteins typically recognize C terminal amino acids and are involved in protein network signaling. GIPC1 may be involved in G protein-linked signaling.
化学信息
分子量Theoretical: 36 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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