DSPE-PEG2000-Azide ammonium is a lipid-based azide compound used in forming micelles for nanoparticle drug delivery. It serves as a click chemistry reagent and includes an azide group that reacts with molecules containing an alkyne group through a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc). Additionally, it can engage in a strain-promoted azide-alkyne cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.