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3-CPMT

Name: 3-CPMT
Brand: TargetMol
SKU: T22508
Price: 822 CNY
Availability: InStock
Rating: 5 (10 reviews)

Synonyms: Wy 2149, SL6057, FC-1, Chlortropbenzyl hydrochloride, 3-[(4-chlorophenyl)-phenylmethoxy]-8-methyl-8-azabicyclo[3.2.1]octane hydrochloride

货号 T22508Cas号 14008-79-8 一键复制产品信息纯度: 99.03%

很棒

3-CPMT (FC-1) 是一种多巴胺摄取抑制剂和一种有效的长效抗组胺剂。

3-CPMT

一键复制产品信息

很棒

纯度: 99.03%

货号 T22508Cas号 14008-79-8

别名 Wy 2149, SL6057, FC-1, Chlortropbenzyl hydrochloride, 3-[(4-chlorophenyl)-phenylmethoxy]-8-methyl-8-azabicyclo[3.2.1]octane hydrochloride

3-CPMT (FC-1) 是一种多巴胺摄取抑制剂和一种有效的长效抗组胺剂。

规格	价格	库存
1 mg	¥ 148	现货
2 mg	¥ 209	现货
5 mg	¥ 343	现货
10 mg	¥ 491	现货
25 mg	¥ 822	现货
50 mg	待询	现货
1 mL x 10 mM (in DMSO)	¥ 369	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

选择批次:

纯度: 99.03%

颜色: 白色

性状: Solid

资源下载: COA HNMR LCMS产品操作手册

产品介绍

3-CPMT AI Summary

3-CPMT shows a diverse range of bioactivities. It exhibits differential inhibitors of proliferation for various strains of Plasmodium falciparum, with potencies from 1122.0 nM to 8912.5 nM and demonstrates antiviral activities by inhibiting SARS-CoV-2 induced cytotoxicity in both Caco-2 cells (9.7% inhibition at 10 µM) and VERO-6 cells (1.16% inhibition at 10 µM). Moreover, it inhibits SARS-CoV-2 3CL-Pro protease by 7.177% at 20 µM concentration. 3-CPMT is also effective in inducing the Erasure of Genomic Imprints (potency: 12589.3 nM), enhancing SMN2 splice variant expression (potency: 35481.3 nM), inhibiting Tau fibril formation (potency: 14125.4 nM), and modulating Lamin A splicing (potency: 5623.4 nM). Additionally, it shows activity against Lassa infection with a 8912.5 nM potency. The compound is a counterscreen for APE1 inhibitors, inhibiting endonuclease IV (potency: 10000.0 nM), and inhibits histone lysine methyltransferase G9a (potency: 22.4 nM) and mammalian selenoprotein thioredoxin reductase 1 (TrxR1) (potency: 23.8 nM). Lastly, it inhibits hERG channel activity with a potency of 501.2 nM..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	3-CPMT (FC-1) is a dopamine uptake inhibitor and a potent long-acting antihistaminic agent.
别名	Wy 2149, SL6057, FC-1, Chlortropbenzyl hydrochloride, 3-[(4-chlorophenyl)-phenylmethoxy]-8-methyl-8-azabicyclo[3.2.1]octane hydrochloride

化学信息

分子量	378.33
分子式	C₂₁H₂₅Cl₂NO
CAS No.	14008-79-8
Smiles	CN1C2CCC1CC(C2)OC(C3=CC=CC=C3)C4=CC=C(C=C4)Cl.Cl
密度	no data available

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息

DMSO: 10 mg/mL (26.43 mM), Sonication is recommended.

Ethanol: 2 mg/mL (5.29 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (2.64 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6432 mL	13.2160 mL	26.4320 mL	132.1598 mL
5 mM	0.5286 mL	2.6432 mL	5.2864 mL	26.4320 mL

DMSO

	1mg	5mg	10mg	50mg
10 mM	0.2643 mL	1.3216 mL	2.6432 mL	13.2160 mL
20 mM	0.1322 mL	0.6608 mL	1.3216 mL	6.6080 mL

该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。