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Plecanatide acetate is a agonist of guanylate cyclase-C (GC-C) receptor( EC50 of 190 nM in T84 cells), and shows anti-inflammatory activity in models of murine colitis.
别名 醋酸普卡那肽
Plecanatide acetate is a agonist of guanylate cyclase-C (GC-C) receptor( EC50 of 190 nM in T84 cells), and shows anti-inflammatory activity in models of murine colitis.

| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 1 mg | ¥ 1,560 | 35日内发货 | |
| 5 mg | ¥ 5,930 | 35日内发货 | |
| 10 mg | ¥ 9,830 | 35日内发货 | |
| 25 mg | ¥ 19,800 | 35日内发货 |
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| 产品描述 | Plecanatide acetate is a agonist of guanylate cyclase-C (GC-C) receptor( EC50 of 190 nM in T84 cells), and shows anti-inflammatory activity in models of murine colitis. |
| 靶点活性 | GC-C (T84 cells):190 nM (EC50) |
| 体外活性 | Plecanatide acetate is a GC-C receptor agonist, binds and activates GC-C receptor(EC50 of 190 nM in T84 cells)[1]. |
| 别名 | 醋酸普卡那肽 |
| 分子量 | 1741.94 |
| 分子式 | C67H108N18O28S4 |
| CAS No. | 1075732-84-1 |
| Smiles | CC(O)=O.[H][C@@]1(CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@]([H])(CSSC[C@]2([H])NC(=O)[C@H](C)NC(=O)C(NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@]([H])(CSSC[C@H](NC(=O)CNC(=O)[C@@]([H])(NC2=O)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(O)=O)NC1=O)C(C)C)C(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)CC(N)=O |@:93| |
| 密度 | no data available |
| Sequence | Asn-Asp-Glu-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu (Disulfide bridge: Cys4-Cys12; Cys7-Cys15) |
| Sequence Short | NDECELCVNVACTGCL (Disulfide bridge: Cys4-Cys12; Cys7-Cys15) |
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. 实际储存温度请以COA为准 |
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