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Anti-Neuroligin-3/NLGN3 Antibody (7G459) 是一种 Rabbit 抗体,靶向 Neuroligin-3/NLGN3。Anti-Neuroligin-3/NLGN3 Antibody (7G459) 可用于 FCM。
Anti-Neuroligin-3/NLGN3 Antibody (7G459) 是一种 Rabbit 抗体,靶向 Neuroligin-3/NLGN3。Anti-Neuroligin-3/NLGN3 Antibody (7G459) 可用于 FCM。
产品描述 | Anti-Neuroligin-3/NLGN3 Antibody (7G459) is a Rabbit antibody targeting Neuroligin-3/NLGN3. Anti-Neuroligin-3/NLGN3 Antibody (7G459) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 7G459 |
交叉反应 | Human |
验证活性 | Flow cytometric analysis of Human NLGN3 expression on U2OS cells. Cells were stained with purified anti-Human NLGN3, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
应用 | FCM |
推荐剂量 | FCM: 1:25-1:100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Neuroligin 3 / NLGN3 (rh Neuroligin 3 / NLGN3; TMPY-01842; Q9NZ94-2; Met1-Ser689). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Neuroligin 3 (NLGN3) is a member of the type-B carboxylesterase/lipase family. Neuroligins (NLGNs) are a family of presumptive postsynaptic cell adhesion molecules. Neuroligins (NLs) constitute a family of cell-surface proteins that interact with neurexins (beta-Nxs), another class of neuronal cell-surface proteins, one of each class functioning together in synapse formation. Neuroligins control the formation and functional balance of excitatory and inhibitory synapses in hippocampal neurons. NLGN1 and NLGN2 isoforms are concentrated at glutamatergic and GABAergic synapses, respectively, but the cellular expression and synaptic localization of the endogenous. NLGN3 was enriched in the brain, where NLGN3 protein levels increased during postnatal development, coinciding with the peak of synaptogenesis. The NLGN3 is a synaptic adhesion molecule that is a shared component of glutamatergic and GABAergic synapses. Mutations in the NLGN3 gene may be associated with autism and Asperger syndrome. |
偶联 | Unconjugated |
免疫原 | Recombinant Human Neuroligin 3 / NLGN3 Protein (TMPY-01842) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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