Name: Anti-EphB2 Antibody
Brand: TargetMol
SKU: T9901A-1274
Rating: 4.5 (1 reviews)

生物活性

产品描述	Anti-EphB2 Antibody represents a highly specialized monoclonal antibody specifically engineered to target the human ephrin type-B receptor 2 (EphB2) with exceptional binding affinity. It effectively facilitates the measurable blockade of EphB2-mediated forward signaling across various preclinical experimental models to evaluate the disruption of tumor cell migration and invasiveness during strictly monitored laboratory observation periods and functional cell survival assays.
靶点活性	EphB2:< 1 nM(Kd)
体外活性	在表达 EphB2 的人癌细胞系中，Anti-EphB2 Antibody 偶联物诱导了快速内吞并产生了强效的细胞杀伤作用，IC50 处于纳摩尔范围 [1]。
体内活性	在人结直肠癌异种移植模型中，通过全身给药方式给予 Anti-EphB2 Antibody 偶联物显著抑制了肿瘤生长 [1]。
别名	抗EphB2抗体
反应种属	Human
应用	ELISA FACS Functional assay
抗体种类	Monoclonal
缓冲液	Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
内毒素	<1.0 EU/mg

抗体信息

同型

IgG1

偶联与修饰

偶联	Unconjugated

抗原信息

Uniprot ID	P29323
靶点	EphB2

储存&溶解度

存储

Anti-EphB2 Antibody