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Anti-kynureninase/KYNU Antibody (4H809)
还可以产品编号 TMAY-03223
Anti-kynureninase/KYNU Antibody (4H809) 是一种 Rabbit 抗体，靶向 kynureninase/KYNU。Anti-kynureninase/KYNU Antibody (4H809) 可用于 WB。
Anti-kynureninase/KYNU Antibody (4H809)
Anti-kynureninase/KYNU Antibody (4H809)
还可以产品编号 TMAY-03223
Anti-kynureninase/KYNU Antibody (4H809) 是一种 Rabbit 抗体，靶向 kynureninase/KYNU。Anti-kynureninase/KYNU Antibody (4H809) 可用于 WB。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-kynureninase/KYNU Antibody (4H809) is a Rabbit antibody targeting kynureninase/KYNU. Anti-kynureninase/KYNU Antibody (4H809) can be used in WB. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 4H809 |
| 交叉反应 | Mouse |
| 验证活性 | Anti-KYNu rabbit monoclonal antibody at 1:500 dilution. -Lane A: NCI-H460 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:52 kDa. -Observed band size:52 kDa(We are unsure as to the identity of these extra bands.) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse KYNU (rM KYNU; TMPY-02418; Q9CXF0; Met1-Ser464). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | KYNU (Kynureninase) is a Protein Coding gene. KYNU is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Genetic studies in the mouse and the human suggest that kynureninase activity may influence blood pressure and renal function. The gene coding kynureninase (KYNU) is also located on chromosome band 2q14-q23, where a linkage peak for essential hypertension was previously detected in the Chinese Han population. The results show that the rare KYNU variant Arg188Gln affects kynureninase activity and are consistent with the hypothesis that this mutation can predispose to essential hypertension. Diseases associated with KYNU include Hydroxykynureninuria and Vertebral, Cardiac, Renal, And Limb Defects Syndrome 2. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse KYNU protein (TMPY-02418) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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