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Anti-Phospho-BRAF (Thr401) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-BRAF (Thr401)。Anti-Phospho-BRAF (Thr401) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-Phospho-BRAF (Thr401) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-BRAF (Thr401)。Anti-Phospho-BRAF (Thr401) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-Phospho-BRAF (Thr401) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BRAF (Thr401). Anti-Phospho-BRAF (Thr401) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit) |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. Cytoplasm. Cell membrane. |
| 组织特异性 | Brain and testis. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. [provided by RefSeq, Aug 2017] |
| 免疫原 | KLH conjugated Synthesised phosphopeptide: human B-Raf around the phosphorylation site of Thr401 |
| 抗原种属 | Human |
| 基因名称 | BRAF |
| 基因ID | |
| 蛋白名称 | Serine/threonine-protein kinase B-raf |
| Uniprot ID | |
| 功能 | Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. |
| 分子量 | Theoretical: 94 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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