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顶部生物活性储存和溶解信息计算器

Anti-Ubiquitin D Antibody (7G418)

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产品编号 TMAC-04189

别名 Ubiquitin-like protein FAT10, UbiquitinD, Ubiquitin like protein FAT10, UBD_HUMAN, UBD 3, Ubd, GABBR1, FAT10, Diubiquitin

Anti-Ubiquitin D Antibody (7G418) 是一种 Rabbit 抗体，靶向 Ubiquitin D。Anti-Ubiquitin D Antibody (7G418) 可用于 ICC,IHC,WB。

Anti-Ubiquitin D Antibody (7G418)

Anti-Ubiquitin D Antibody (7G418)

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Rating icon 还可以
产品编号 TMAC-04189 别名 Ubiquitin-like protein FAT10, UbiquitinD, Ubiquitin like protein FAT10, UBD_HUMAN, UBD 3, Ubd, GABBR1, FAT10, Diubiquitin

Anti-Ubiquitin D Antibody (7G418) 是一种 Rabbit 抗体，靶向 Ubiquitin D。Anti-Ubiquitin D Antibody (7G418) 可用于 ICC,IHC,WB。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-Ubiquitin D Antibody (7G418) is a Rabbit antibody targeting Ubiquitin D. Anti-Ubiquitin D Antibody (7G418) can be used in ICC,IHC,WB.
别名Ubiquitin-like protein FAT10, UbiquitinD, Ubiquitin like protein FAT10, UBD_HUMAN, UBD 3, Ubd, GABBR1, FAT10, Diubiquitin
Ig Type
IgG
克隆号
7G418
交叉反应
Human,Mouse
验证活性
1. Western blot analysis of Ubiquitin D on Hela cells lysates using anti-Ubiquitin D antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Ubiquitin D antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Ubiquitin D antibody. Counter stained with hematoxylin.
4. ICC staining Ubiquitin D in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. ICC staining Ubiquitin D in F9 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. ICC staining Ubiquitin D in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
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应用ICCIHCWB
推荐剂量
WB: 1:1000-2000; IHC: 1:50-200; ICC: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景FAT10, also designated Ubiquitin D or Diubiquitin, is a 165 amino acid protein encoded in the major histocompatibility complex (MHC) that consists of two domains which share significant homology with ubiquitin. Each domain contains two cysteines, along with a free C-terminal diglycine motif required for FAT10 conjugate formation. FAT10 is inducible by interferon-g and tumor necrosis factor a (TNF?). The FAT10 protein interacts with MAD2, a component of the spindle checkpoint, and plays a role in antigen presentation, cytokine response, apoptosis and mitosis. It may also regulate cell growth during dendritic cell or B cell activation and development. FAT10 mRNA is expressed mainly in some dendritic cells and lymphoblastoid lines and in other specific cells subsequent to interferon-g induction. The human FAT10 gene, designated UBD, maps to chromosome 6p21.3 and is overexpressed in the tumors of various epithelial cancers.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
O15205
化学信息
分子量Theoretical: 18 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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