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Anti-BRMS1 Antibody (4O811)

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货号 TMAB-03222

Anti-BRMS1 Antibody (4O811) 是一种 Rabbit 抗体,靶向 BRMS1。Anti-BRMS1 Antibody (4O811) 可用于 ICC/IF, IF, IHC-Fr, IHC-P。

Anti-BRMS1 Antibody (4O811)

Anti-BRMS1 Antibody (4O811)

一键复制产品信息
Rating icon 还可以
货号 TMAB-03222

Anti-BRMS1 Antibody (4O811) 是一种 Rabbit 抗体,靶向 BRMS1。Anti-BRMS1 Antibody (4O811) 可用于 ICC/IF, IF, IHC-Fr, IHC-P。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍


生物活性
产品描述
Anti-BRMS1 Antibody (4O811) is a Rabbit antibody targeting BRMS1. Anti-BRMS1 Antibody (4O811) can be used in ICC/IF, IF, IHC-Fr, IHC-P.
Ig Type
IgG
克隆号
4O811
反应种属
Human
应用ICC/IFIFIHC-FrIHC-P
推荐剂量
ICC/IF=1:50-200; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Predominantly nuclear.
组织特异性Expression levels are higher in term placentas than in early placentas. Low levels of expression observed in normal pregnancies and in molar pregnancies.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.
抗原信息
免疫原
A synthesized peptide: human BRMS1
抗原种属
Human
基因名称
BRMS1
基因ID
蛋白名称
Breast cancer metastasis-suppressor 1
Uniprot ID
功能
Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.
化学信息
分子量Theoretical: 28 kDa. Actual: 28 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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