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Anti-BRMS1 Antibody (4O811) 是一种 Rabbit 抗体,靶向 BRMS1。Anti-BRMS1 Antibody (4O811) 可用于 ICC/IF, IF, IHC-Fr, IHC-P。
Anti-BRMS1 Antibody (4O811) 是一种 Rabbit 抗体,靶向 BRMS1。Anti-BRMS1 Antibody (4O811) 可用于 ICC/IF, IF, IHC-Fr, IHC-P。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 780 | 5日内发货 | |
| 50 μL | ¥ 1,380 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
| 产品描述 | Anti-BRMS1 Antibody (4O811) is a Rabbit antibody targeting BRMS1. Anti-BRMS1 Antibody (4O811) can be used in ICC/IF, IF, IHC-Fr, IHC-P. |
| Ig Type | IgG |
| 克隆号 | 4O811 |
| 反应种属 | Human |
| 应用 | ICC/IFIFIHC-FrIHC-P |
| 推荐剂量 | ICC/IF=1:50-200; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. Cytoplasm. Predominantly nuclear. |
| 组织特异性 | Expression levels are higher in term placentas than in early placentas. Low levels of expression observed in normal pregnancies and in molar pregnancies. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma. |
| 免疫原 | A synthesized peptide: human BRMS1 |
| 抗原种属 | Human |
| 基因名称 | BRMS1 |
| 基因ID | |
| 蛋白名称 | Breast cancer metastasis-suppressor 1 |
| Uniprot ID | |
| 功能 | Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma. |
| 分子量 | Theoretical: 28 kDa. Actual: 28 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |