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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-GLCNE Antibody (4K747)

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货号 TMAB-06500

Anti-GLCNE Antibody (4K747) 是一种 Rabbit 抗体，靶向 GLCNE。Anti-GLCNE Antibody (4K747) 可用于 WB,ICC/IF。

Anti-GLCNE Antibody (4K747)

Anti-GLCNE Antibody (4K747)

一键复制产品信息
Rating icon 还可以
货号 TMAB-06500

Anti-GLCNE Antibody (4K747) 是一种 Rabbit 抗体，靶向 GLCNE。Anti-GLCNE Antibody (4K747) 可用于 WB,ICC/IF。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-GLCNE Antibody (4K747) is a Rabbit antibody targeting GLCNE. Anti-GLCNE Antibody (4K747) can be used in WB,ICC/IF.
Ig Type
IgG
克隆号
4K747
反应种属
Human
应用WBICC/IF
推荐剂量
WB: 1:500-2000; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasmic
组织特异性Highest expression in liver and placenta. Also found in heart, brain, lung, kidney, skeletal muscle and pancreas. Isoform 1 is expressed in heart, brain, kidney, liver, placenta, lung, spleen, pancreas, skeletal muscle and colon. Isoform 2 is expressed mainly in placenta, but also in brain, kidney, liver, lung, pancreas and colon. Isoform 3 is expressed at low level in kidney, liver, placenta and colon.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Bifunctional enzyme that possesses both UDP-N-acetylglucosamine 2-epimerase and N-acetylmannosamine kinase activities, and serves as the initiator of the biosynthetic pathway leading to the production of N-acetylneuraminic acid (NeuAc), a critical precursor in the synthesis of sialic acids. By catalyzing this pivotal and rate-limiting step in sialic acid biosynthesis, this enzyme assumes a pivotal role in governing the regulation of cell surface sialylation.
抗原信息
免疫原
A synthesized peptide: human GNE
抗原种属
Human
基因名称
GNE
基因ID
10020
蛋白名称
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
Uniprot ID
Q9Y223
功能
Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Plays an essential role in early development (By similarity). Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells.
化学信息
分子量Theoretical: 79 kDa. Actual: 75 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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