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顶部生物活性储存和溶解信息计算器

Anti-FGF-19 Antibody (2F284)

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Anti-FGF-19 Antibody (2F284)
产品编号 TMAY-02289
别名 fibroblast growth factor 19, FGF19

Anti-FGF-19 Antibody (2F284) 是一种 Rabbit 抗体，靶向 FGF-19。Anti-FGF-19 Antibody (2F284) 可用于 ELISA。

Anti-FGF-19 Antibody (2F284)
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Anti-FGF-19 Antibody (2F284)

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Anti-FGF-19 Antibody (2F284)
产品编号 TMAY-02289 别名 fibroblast growth factor 19, FGF19

Anti-FGF-19 Antibody (2F284) 是一种 Rabbit 抗体，靶向 FGF-19。Anti-FGF-19 Antibody (2F284) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,279
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产品介绍

生物活性
产品描述
Anti-FGF-19 Antibody (2F284) is a Rabbit antibody targeting FGF-19. Anti-FGF-19 Antibody (2F284) can be used in ELISA.
别名fibroblast growth factor 19, FGF19
Ig Type
Rabbit IgG
克隆号
2F284
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human FGF19 / FGF-19 (rh FGF19 / FGF-19; TMPY-02907; O95750-1; Phe27-Lys216).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF19 interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by KL, KLB and heparan sulfate glycosaminoglycans that function as coreceptors. It interacts with KL and KLB directly. However, it interacts with FGFR4 in the presence of heparin, KL or KLB. FGF19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. It also stimulates glucose uptake in adipocytes.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human FGF19 / FGF-19 protein (TMPY-02907)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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关键词

FGF-19FGF 19

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