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Anti-FGF-19 Antibody (2F284)
还可以产品编号 TMAY-02289
Anti-FGF-19 Antibody (2F284) 是一种 Rabbit 抗体，靶向 FGF-19。Anti-FGF-19 Antibody (2F284) 可用于 ELISA。
Anti-FGF-19 Antibody (2F284)
Anti-FGF-19 Antibody (2F284)
还可以产品编号 TMAY-02289
Anti-FGF-19 Antibody (2F284) 是一种 Rabbit 抗体，靶向 FGF-19。Anti-FGF-19 Antibody (2F284) 可用于 ELISA。
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抗原信息
| 产品描述 | Anti-FGF-19 Antibody (2F284) is a Rabbit antibody targeting FGF-19. Anti-FGF-19 Antibody (2F284) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 2F284 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human FGF19 / FGF-19 (rh FGF19 / FGF-19; TMPY-02907; O95750-1; Phe27-Lys216). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF19 interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by KL, KLB and heparan sulfate glycosaminoglycans that function as coreceptors. It interacts with KL and KLB directly. However, it interacts with FGFR4 in the presence of heparin, KL or KLB. FGF19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. It also stimulates glucose uptake in adipocytes. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human FGF19 / FGF-19 protein (TMPY-02907) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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