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Anti-NOV/CCN3 Antibody (4V520)
还可以产品编号 TMAY-00536
Anti-NOV/CCN3 Antibody (4V520) 是一种 Mouse 抗体，靶向 NOV/CCN3。Anti-NOV/CCN3 Antibody (4V520) 可用于 ELISA。
Anti-NOV/CCN3 Antibody (4V520)
Anti-NOV/CCN3 Antibody (4V520)
还可以产品编号 TMAY-00536
Anti-NOV/CCN3 Antibody (4V520) 是一种 Mouse 抗体，靶向 NOV/CCN3。Anti-NOV/CCN3 Antibody (4V520) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-NOV/CCN3 Antibody (4V520) is a Mouse antibody targeting NOV/CCN3. Anti-NOV/CCN3 Antibody (4V520) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG |
| 克隆号 | 4V520 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human NOV / CCN3 (rh NOV; TMPY-01307; NP_002505.1; Met 1-Met 357). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Protein NOV homolog, also known as Nephroblastoma-overexpressed gene protein homolog, NOV, and CCN3, is a putative ligand for integrin receptors, is tightly associated with the extracellular matrix, and mediates diverse cellular functions, including cell adhesion and proliferation. CCN3 has been shown to negatively regulate growth although it promotes migration in a cell type-specific manner. This secreted protein belongs to the CCN family, and its expression was observed in a broad variety of tissues from the early stage of development, and altered expression of CCN3 has been observed in a variety of tumors, including hepatocellular carcinomas, Wilm's tumors, Ewing's sarcomas, gliomas, rhabdomyosarcomas, and adrenocortical carcinomas. Mature CCN3 protein has five distinct modules and truncated protein variants with altered function are found in many cancers. CCN3 acts through the core stem cell signaling pathways including Notch and Bone Morphogenic Protein, connecting CCN3 with the modulation of self-renewal and maturation of some cell lineages including hematopoietic, osteogenic, and chondrogenic. CCN3 may affect the extracellular environment of the niche for hematopoietic stem cells. CCN3 has emerged as a key player in stem cell regulation, hematopoiesis, and a crucial component within the bone marrow microenvironment. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human NOV protein (TMPY-01307) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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