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Anti-Phospho-PYK2 (Tyr579) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-PYK2 (Tyr579)。Anti-Phospho-PYK2 (Tyr579) Polyclonal Antibody 可用于 WB,IHC。
Anti-Phospho-PYK2 (Tyr579) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-PYK2 (Tyr579)。Anti-Phospho-PYK2 (Tyr579) Polyclonal Antibody 可用于 WB,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,235 | 5日内发货 |
产品描述 | Anti-Phospho-PYK2 (Tyr579) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PYK2 (Tyr579). Anti-Phospho-PYK2 (Tyr579) Polyclonal Antibody can be used in WB,IHC. |
别名 | PYK2 (p-Y579), PYK2 (p-Tyr579), p-PYK2 (Y579), p-PYK2 (Tyr579) |
Ig Type | IgG |
交叉反应 | Human,Mouse |
验证活性 | 1. Western blot analysis of extracts from 3T3 cells (Lane 2) and HepG2 cells (Lane 3), using PYK2 (Phospho-Tyr579) Antibody TMAC-03475. The lane on the left is treated with antigen-specific peptide. 2. Immunohistochemical analysis of paraffin-embedded human brain tissue using PYK2 (Phospho-Tyr579) antibody TMAC-03475 (left) or the same antibody preincubated with blocking peptide (right). |
应用 | |
推荐剂量 | WB: 1:500-1000; IHC: 1:50-100 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. May represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage-gated potassium channel protein Kv1.2. Its activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity. Involved in osmotic stress-dependent SNCA 'Tyr-125' phosphorylation. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of tyrosine 579(E-D-Y(p)-Y-K) derived from Human PYK2 |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 116 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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