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顶部生物活性储存和溶解信息计算器

Anti-DKK1 Antibody (4P933)

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产品编号 TMAH-00349

别名 SK, hDkk-1, hDkk1, Dkk-1, Dkk1, Dickkopf-related 1, Dickkopf-1

Anti-DKK1 Antibody (4P933) 是一种抗体，靶向 DKK1。Anti-DKK1 Antibody (4P933) 可用于 ELISA。

Anti-DKK1 Antibody (4P933)

Anti-DKK1 Antibody (4P933)

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Rating icon 还可以
产品编号 TMAH-00349 别名 SK, hDkk-1, hDkk1, Dkk-1, Dkk1, Dickkopf-related 1, Dickkopf-1

Anti-DKK1 Antibody (4P933) 是一种抗体，靶向 DKK1。Anti-DKK1 Antibody (4P933) 可用于 ELISA。

规格价格库存数量
50 μL
¥ 1,305
5日内发货
100 μL
¥ 2,195
5日内发货
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产品介绍

生物活性
产品描述
Anti-DKK1 Antibody (4P933) is an antibody targeting DKK1. Anti-DKK1 Antibody (4P933) can be used in ELISA.
别名SK, hDkk-1, hDkk1, Dkk-1, Dkk1, Dickkopf-related 1, Dickkopf-1
Ig Type
Human IgG1
克隆号
4P933
交叉反应
Human
验证活性
The Binding Activity of Human DKK1 with Anti-DKK1 Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human DKK1 at 2 μg/mL can bind Anti-DKK1 recombinant antibody, the EC50 is 1.283-2.544 ng/mL.
应用ELISA
抗体种类
Monoclonal
亚细胞定位Secreted.
组织特异性Placenta.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
研究背景Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human DKK1 Protein
抗原种属
Human
基因名称
DKK1
基因ID
22943
Uniprot ID
O94907
研究领域
Cardiovascular, Developmental biology, Immunology, Stem cells
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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