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Anti-ADAM17 Polyclonal Antibody 2

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货号 TMAB-02283

Anti-ADAM17 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 ADAM17。Anti-ADAM17 Polyclonal Antibody 2 可用于 WB。

Anti-ADAM17 Polyclonal Antibody 2

Anti-ADAM17 Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-02283

Anti-ADAM17 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 ADAM17。Anti-ADAM17 Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-ADAM17 Polyclonal Antibody 2 is a Rabbit antibody targeting ADAM17. Anti-ADAM17 Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane.
组织特异性Ubiquitously expressed. Expressed at highest levels in adult heart, placenta, skeletal muscle, pancreas, spleen, thymus, prostate, testes, ovary and small intestine, and in fetal brain, lung, liver and kidney.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq].
抗原信息
免疫原
KLH conjugated synthetic peptide: human ADAM17
抗原种属
Human
基因名称
ADAM17
基因ID
6868
蛋白名称
Disintegrin and metalloproteinase domain-containing protein 17
Uniprot ID
P78536
功能
Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Also involved in the activation of Notch pathway (By similarity).
化学信息
分子量Theoretical: 91 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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