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别名 TSR-I, SKR3, ORW2, HHT2, HHT, ALK-1, ALK1, ACVRLK1, ACVRL1, activin A receptor type II-like 1
Anti-ALK-1 Antibody (3M872) 是一种抗体,靶向 ALK-1。Anti-ALK-1 Antibody (3M872) 可用于 ELISA。
Anti-ALK-1 Antibody (3M872) 是一种抗体,靶向 ALK-1。Anti-ALK-1 Antibody (3M872) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,305 | 5日内发货 | |
| 100 μL | ¥ 2,190 | 5日内发货 |
| 产品描述 | Anti-ALK-1 Antibody (3M872) is an antibody targeting ALK-1. Anti-ALK-1 Antibody (3M872) can be used in ELISA. |
| 别名 | TSR-I, SKR3, ORW2, HHT2, HHT, ALK-1, ALK1, ACVRLK1, ACVRL1, activin A receptor type II-like 1 |
| Ig Type | Human IgG2 |
| 克隆号 | 3M872 |
| 交叉反应 | Human |
| 验证活性 | 1. The Binding Activity of Human ACVRL1 with Anti-ACVRL1 recombinant antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ACVRL1 at 2 μg/mL can bind Anti-ACVRL1 recombinant antibody, the EC50 is 2.417-2.971ng/mL. 2. The Binding Activity of Cynomolgus ACVRL1 with Anti-ACVRL1 recombinant antibody Activity: Measured by its binding ability in a functional ELISA.Immobilized Cynomolgus ACVRL1 at 2 μg/mL can bind Anti-ACVRL1 recombinant antibody. The EC50 is 6.893-8.194 ng/mL. |
| 应用 | ELISA |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| 研究背景 | Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human ACVRL1 Protein |
| 抗原种属 | Human |
| 基因名称 | ACVRL1 |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Immunology, Stem cells |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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