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Anti-CLPS Antibody (4Z722) 是一种 Rabbit 抗体,靶向 CLPS。Anti-CLPS Antibody (4Z722) 可用于 ELISA,IHC-P。
Anti-CLPS Antibody (4Z722) 是一种 Rabbit 抗体,靶向 CLPS。Anti-CLPS Antibody (4Z722) 可用于 ELISA,IHC-P。
产品描述 | Anti-CLPS Antibody (4Z722) is a Rabbit antibody targeting CLPS. Anti-CLPS Antibody (4Z722) can be used in ELISA,IHC-P. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 4Z722 |
交叉反应 | Human |
验证活性 | Immunochemical staining of human CLPS in human pancreas with rabbit monoclonal antibody (1:500, formalin-fixed paraffin embedded sections). |
应用 | ELISA,IHC-P |
推荐剂量 | ELISA: 1:5000-1:10000; IHC-P: 1:250-1:1000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CLPS / Colipase (rh CLPS / Colipase; TMPY-02846; P04118; Met1-Gln112). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Colipase belongs to the colipase family. Structural studies of the complex and of colipase alone have revealed the functionality of its architecture. It is a small protein with five conserved disulphide bonds. Structural analogies have been recognised between a developmental protein, the pancreatic lipase C-terminal domain, the N-terminal domains of lipoxygenases and the C-terminal domain of alpha-toxin. Colipase can only be detected in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Colipase allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase. Colipase is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilising as active conformation and considerably increasing the overall hydrophobic binding site. |
偶联 | Unconjugated |
免疫原 | Recombinant Human CLPS / Colipase protein (TMPY-02846) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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