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Anti-CLPS Antibody (4Z722)

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产品编号 TMAY-02613

Anti-CLPS Antibody (4Z722) 是一种 Rabbit 抗体,靶向 CLPS。Anti-CLPS Antibody (4Z722) 可用于 ELISA,IHC-P。

Anti-CLPS Antibody (4Z722)

Anti-CLPS Antibody (4Z722)

Rating icon 还可以
产品编号 TMAY-02613

Anti-CLPS Antibody (4Z722) 是一种 Rabbit 抗体,靶向 CLPS。Anti-CLPS Antibody (4Z722) 可用于 ELISA,IHC-P。

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产品介绍

生物活性
产品描述
Anti-CLPS Antibody (4Z722) is a Rabbit antibody targeting CLPS. Anti-CLPS Antibody (4Z722) can be used in ELISA,IHC-P.
Ig Type
Monoclonal Rabbit IgG
克隆号
4Z722
交叉反应
Human
验证活性
Immunochemical staining of human CLPS in human pancreas with rabbit monoclonal antibody (1:500, formalin-fixed paraffin embedded sections).
应用
ELISA,IHC-P
推荐剂量
ELISA: 1:5000-1:10000; IHC-P: 1:250-1:1000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human CLPS / Colipase (rh CLPS / Colipase; TMPY-02846; P04118; Met1-Gln112).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Colipase belongs to the colipase family. Structural studies of the complex and of colipase alone have revealed the functionality of its architecture. It is a small protein with five conserved disulphide bonds. Structural analogies have been recognised between a developmental protein, the pancreatic lipase C-terminal domain, the N-terminal domains of lipoxygenases and the C-terminal domain of alpha-toxin. Colipase can only be detected in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Colipase allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase. Colipase is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilising as active conformation and considerably increasing the overall hydrophobic binding site.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human CLPS / Colipase protein (TMPY-02846)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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