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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PGGT1A Polyclonal Antibody

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货号 TMAB-10244

Anti-PGGT1A Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PGGT1A。Anti-PGGT1A Polyclonal Antibody 可用于 WB。

Anti-PGGT1A Polyclonal Antibody

Anti-PGGT1A Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-10244

Anti-PGGT1A Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PGGT1A。Anti-PGGT1A Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-PGGT1A Polyclonal Antibody is a Rabbit antibody targeting PGGT1A. Anti-PGGT1A Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasmic
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景FNTA, also known as CAAX farnesyltransferase (FTase), attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the so-called CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This type of posttranslational modification provides a mechanism for membrane localization of proteins that lack a transmembrane domain. This enzyme has the remarkable property of farnesylating peptides as short as four residues in length that conform to the CAAX consensus sequence. FNTA is also a specific cytoplasmic interactor of the transforming growth factor-beta and activin type I receptors. It is likely to be a key component of the signaling pathway which involves p21ras, an important substrate for farnesyltransferase.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PGGT1A/FNTA
抗原种属
Human
基因名称
FNTA
基因ID
2339
蛋白名称
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
Uniprot ID
P49354
功能
Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate. Through RAC1 prenylation and activation may positively regulate neuromuscular junction development downstream of MUSK (By similarity).
化学信息
分子量Theoretical: 44 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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