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Anti-E2F6 Antibody (3B498)

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货号 TMAB-05396

Anti-E2F6 Antibody (3B498) 是一种 Rabbit 抗体,靶向 E2F6。Anti-E2F6 Antibody (3B498) 可用于 WB,ICC/IF,FCM。

Anti-E2F6 Antibody (3B498)

Anti-E2F6 Antibody (3B498)

一键复制产品信息
Rating icon 还可以
货号 TMAB-05396

Anti-E2F6 Antibody (3B498) 是一种 Rabbit 抗体,靶向 E2F6。Anti-E2F6 Antibody (3B498) 可用于 WB,ICC/IF,FCM。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍


生物活性
产品描述
Anti-E2F6 Antibody (3B498) is a Rabbit antibody targeting E2F6. Anti-E2F6 Antibody (3B498) can be used in WB,ICC/IF,FCM.
Ig Type
IgG
克隆号
3B498
反应种属
Human
应用WBICC/IFFCM
推荐剂量
WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Expressed in all tissues examined. Highest levels in placenta, skeletal muscle, heart, ovary, kidney, small intestine and spleen.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F-6 lacks the transcriptional activation and pocket protein binding domains.
抗原信息
免疫原
A synthesized peptide: human E2F6
抗原种属
Human
基因名称
E2F6
基因ID
蛋白名称
Transcription factor E2F6
Uniprot ID
功能
Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overexpression delays the exit of cells from the S-phase.
化学信息
分子量Theoretical: 32 kDa. Actual: 32 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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