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顶部生物活性储存和溶解信息计算器

Anti-Phospho-MEK5 (Ser311+Thr315) Polyclonal Antibody

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产品编号 TMAB-10992

Anti-Phospho-MEK5 (Ser311+Thr315) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-MEK5 (Ser311+Thr315)。Anti-Phospho-MEK5 (Ser311+Thr315) Polyclonal Antibody 可用于 WB。

Anti-Phospho-MEK5 (Ser311+Thr315) Polyclonal Antibody

Anti-Phospho-MEK5 (Ser311+Thr315) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
产品编号 TMAB-10992

Anti-Phospho-MEK5 (Ser311+Thr315) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-MEK5 (Ser311+Thr315)。Anti-Phospho-MEK5 (Ser311+Thr315) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-MEK5 (Ser311+Thr315) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MEK5 (Ser311+Thr315). Anti-Phospho-MEK5 (Ser311+Thr315) Polyclonal Antibody can be used in WB.
Ig Type
IgG
交叉反应
Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Expressed in many adult tissues. Abundant in heart and skeletal muscle.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景MEK5 is a dual specificity protein kinase belonging to thr Ser/Thr protein kinase family, (MAP kinase kinase family). It is activated by phosphorylation on Ser/Thr by MAP kinase kinases and interacts specifically with ERK5, and not with another MAP kinase like P38. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). It is not phosphorylated by RAFA, RAFB or RAFC and it may interact with GTPases such as CDC42. The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. MEK5 is expressed in many adult tissues and is most abundant in heart and skeletal muscle.
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human MEK5 around the phosphorylation site of Ser311+Thr315
抗原种属
Human
基因名称
MAP2K5
基因ID
5607
蛋白名称
Dual specificity mitogen-activated protein kinase kinase 5
Uniprot ID
Q13163
功能
Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appear to play a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis.
化学信息
分子量Theoretical: 49 kDa.
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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