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Anti-SFRP1 Antibody (3A606)
还可以产品编号 TMAY-01056
别名 secreted frizzled-related protein 1, SARP2, FrzA, FRP-1, FRP1, FRP
Anti-SFRP1 Antibody (3A606) 是一种 Rabbit 抗体，靶向 SFRP1。Anti-SFRP1 Antibody (3A606) 可用于 ELISA。
Anti-SFRP1 Antibody (3A606)
Anti-SFRP1 Antibody (3A606)
还可以产品编号 TMAY-01056 别名 secreted frizzled-related protein 1, SARP2, FrzA, FRP-1, FRP1, FRP
Anti-SFRP1 Antibody (3A606) 是一种 Rabbit 抗体，靶向 SFRP1。Anti-SFRP1 Antibody (3A606) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,289 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-SFRP1 Antibody (3A606) is a Rabbit antibody targeting SFRP1. Anti-SFRP1 Antibody (3A606) can be used in ELISA. |
| 别名 | secreted frizzled-related protein 1, SARP2, FrzA, FRP-1, FRP1, FRP |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 3A606 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human SFRP1 (rh SFRP1; TMPY-00918; NP_003003.3; Met1-Lys314). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Secreted frizzled-related protein 1, also known as sFRP1, is a 35 kDa prototypical member of the SFRP family. SFRP family consists of five secreted glycoproteins in humans acting as extracellular signaling ligands. Each is approximately 3 amino acids in length and contains a cysteine-rich domain (CRD) that shares 3-5% sequence homology with the CRD of Frizzled (Fz) receptors, a putative signal sequence, and a conserved hydrophilic carboxy-terminal domain. SFRPs act as soluble modulators of Wnt signaling, counteracting Wnt-induced effects at high concentrations and promoting them at lower concentrations. SFRPs are able to bind Wnt proteins and Fz receptors in the extracellular compartment. The interaction between SFRPs and Wnt proteins prevents the latter from binding the Fz receptors. The Wnt pathway plays a key role in embryonic development, cell differentiation and cell proliferation. The deregulation of this critical developmental pathway occurs in several human tumor entities. Mouse sFRP1 is highly expressed in kidney and embryonic heart, as well as in the eye, where it is principally localized to the ciliary body and the lens epithelium. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human SFRP1 Protein (TMPY-00918) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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