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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-GPRC5B Polyclonal Antibody

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货号 TMAB-06734

Anti-GPRC5B Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GPRC5B。Anti-GPRC5B Polyclonal Antibody 可用于 FCM。

Anti-GPRC5B Polyclonal Antibody

Anti-GPRC5B Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-06734

Anti-GPRC5B Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GPRC5B。Anti-GPRC5B Polyclonal Antibody 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-GPRC5B Polyclonal Antibody is a Rabbit antibody targeting GPRC5B. Anti-GPRC5B Polyclonal Antibody can be used in FCM.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用FCM
推荐剂量
FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane. Cytoplasmic vesicle membrane. Localized in the plasma membrane and perinuclear vesicles.
组织特异性Expression is high in kidney, pancreas, and testis, medium in brain, heart, prostate, small intestine, and spleen, low in liver, placenta, skeletal muscle, colon, ovary, and thymus, and not detectable in lung and peripheral leukocyte. According to PubMed:10945465, highly expressed in most brain areas examined, with the highest levels observed in corpus callosum, caudate nucleus, putamen, substantia nigra, thalamus, hippocampus, and spinal chord as well as in dorsal root ganglia (DRG). In the periphery, expression levels are relatively low, compared to the CNS, with the strongest expression detected in pancreas, testis, uterus, and stomach.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景GPRC5B (G protein-coupled receptor family C group 5 member B, retinoic acid-induced gene 2 protein) is a 403 amino acid protein encoded by the human GPRC5B gene. GPRC5B is an orphan receptor member of the G protein-coupled receptor 3 family. G protein-coupled receptors (GPCRs or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. Key roles for G protein-coupled receptors include control of protein maturation and cell surface delivery, and providing the correct framework for interactions with both heterotrimeric G proteins and arrestins to allow signal generation and termination. This retinoic acid-inducible G protein-coupled receptor provides evidence for a possible interaction between retinoid and G protein signaling pathways. GPRC5B is highly expressed in kidney, pancreas and testis, and has moderate expression in brain, heart, prostate, small intestine and spleen.
抗原信息
免疫原
KLH conjugated synthetic peptide: human G protein coupled receptor family C group 1 member B
抗原种属
Human
基因名称
GPRC5B
基因ID
51704
蛋白名称
G-protein coupled receptor family C group 5 member B
Uniprot ID
Q9NZH0
功能
Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.
化学信息
分子量Theoretical: 42 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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