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Anti-SEMA4D Antibody (1D998) 是一种 Rabbit 抗体,靶向 SEMA4D。Anti-SEMA4D Antibody (1D998) 可用于 FCM。
Anti-SEMA4D Antibody (1D998) 是一种 Rabbit 抗体,靶向 SEMA4D。Anti-SEMA4D Antibody (1D998) 可用于 FCM。
产品描述 | Anti-SEMA4D Antibody (1D998) is a Rabbit antibody targeting SEMA4D. Anti-SEMA4D Antibody (1D998) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 1D998 |
交叉反应 | Mouse |
验证活性 | Flow cytometric analysis of SEMA4D(CD100) expression on BABL/c splenocytes. Cells were stained with purified anti-Mouse SEMA4D(CD100), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
应用 | FCM |
推荐剂量 | FCM: 1:25-1:100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Semaphorin 4D / SEMA4D / CD100 (rM Semaphorin 4D / SEMA4D / CD100; TMPY-01836; NP_038688.2; Met1-Arg733). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Semaphorin 4D (SEMA4D or CD100) is a member of the semaphorin family of proteins and an important mediator of the movement and differentiation of multiple cell types, including those of the immune, vascular, and nervous systems. VEGF and SEMA4D had a positive correlation with the malignant degree of ovarian cancer, and SEMA4D can serve as an independent prognostic factor. SEMA4D was the first semaphorin described to have immune functions and serves important roles in T cell priming, antibody production, and cell-to-cell adhesion. Proteolytic cleavage of SEMA4D from the cell surface gives rise to a soluble fragment of SEMA4D (sSEMA4D). Similar to the transmembranal form, sSEMA4D is thought to have immunoregulatory properties. |
偶联 | Unconjugated |
其他可选修饰符 | APC/FITC/PE |
可提供抗体种类 | 4 |
免疫原 | Recombinant Mouse Semaphorin 4D / SEMA4D / CD100 protein (TMPY-01836) |
抗原种属 | Mouse |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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