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Anti-IL-20RA Antibody (7Q925)

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产品编号 TMAY-00758

Anti-IL-20RA Antibody (7Q925) 是一种 Rabbit 抗体,靶向 IL-20RA。Anti-IL-20RA Antibody (7Q925) 可用于 ELISA,IHC-P。

Anti-IL-20RA Antibody (7Q925)

Anti-IL-20RA Antibody (7Q925)

Rating icon 还可以
产品编号 TMAY-00758

Anti-IL-20RA Antibody (7Q925) 是一种 Rabbit 抗体,靶向 IL-20RA。Anti-IL-20RA Antibody (7Q925) 可用于 ELISA,IHC-P。

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产品介绍

生物活性
产品描述
Anti-IL-20RA Antibody (7Q925) is a Rabbit antibody targeting IL-20RA. Anti-IL-20RA Antibody (7Q925) can be used in ELISA,IHC-P.
Ig Type
Monoclonal Rabbit IgG
克隆号
7Q925
交叉反应
Human
验证活性
Immunochemical staining of human IL20Ra in human skin with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to stratified squamous epithelium.
应用
ELISA,IHC-P
推荐剂量
ELISA: 1:1000-1:2000; IHC-P: 1:100-1:500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human IL20RA / IL-20RA (rh IL20RA / IL-20RA; TMPY-01054; NP_055247.3; Met 1-Lys 250).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Interleukin 20 receptor, alpha subunit (IL20RA/IL-20RA) also known as IL-20 receptor subunit alpha, Cytokine receptor class-II member 8, interleukin-20 receptor I, and interleukin-20 receptor subunit alpha, is a subunit for the interleukin-20 receptor. IL20RA/IL-20RA belongs to the type II cytokine receptor family. This cytokine is a receptor for interleukin 20 (IL20), a cytokine that may be involved in the epidermal function. The receptor of IL20 is a heterodimeric receptor complex consisting of this protein and interleukin 20 receptor beta (IL20B). IL20RA forms heterodimer with IL20RB and the complex serves as a receptor for IL19, IL20, and IL24. All three are capable of signaling through the IL-20RA/IL-20RB complex. The ligand binding to receptor B creating a high-affinity binding site for receptor A which is recruited to complete the complex. Besides, IL20RA also forms a heterodimer with the unique and specific receptor IL10RB and functions as the receptor for IL26. IL20RA is widely expressed with the highest levels in skin, testis, and brain. The expression of both IL20RA and IL20RB is found to be upregulated in psoriatic skin lesions on keratinocytes.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human IL20RA / IL-20RA protein (TMPY-01054)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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