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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-HIF Prolyl Hydroxylases Polyclonal Antibody 2

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货号 TMAB-07024

Anti-HIF Prolyl Hydroxylases Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 HIF Prolyl Hydroxylases。Anti-HIF Prolyl Hydroxylases Polyclonal Antibody 2 可用于 WB。

Anti-HIF Prolyl Hydroxylases Polyclonal Antibody 2

Anti-HIF Prolyl Hydroxylases Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-07024

Anti-HIF Prolyl Hydroxylases Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 HIF Prolyl Hydroxylases。Anti-HIF Prolyl Hydroxylases Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
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100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

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产品描述
Anti-HIF Prolyl Hydroxylases Polyclonal Antibody 2 is a Rabbit antibody targeting HIF Prolyl Hydroxylases. Anti-HIF Prolyl Hydroxylases Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Pig)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane; Single-pass type II membrane protein.
组织特异性Widely expressed with highest levels in adult pancreas, heart, skeletal muscle, brain, placenta, kidney and adrenal gland. Expressed at lower levels in epiphyseal cartilage and in fibroblasts.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human HIF Prolyl Hydroxylases
抗原种属
Human
基因名称
P4HTM
基因ID
54681
蛋白名称
Transmembrane prolyl 4-hydroxylase
Uniprot ID
Q9NXG6
功能
Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
化学信息
分子量Theoretical: 57 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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