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Anti-Mucin-4/MUC4 Antibody (8K130)

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Anti-Mucin-4/MUC4 Antibody (8K130)
产品编号 TMAC-02683
别名 Testis mucin, Pancreatic adenocarcinoma mucin, Mucin-4, MUC-4, Muc4, Ascites sialoglycoprotein (ASGP)

Anti-Mucin-4/MUC4 Antibody (8K130) 是一种 Rabbit 抗体,靶向 Mucin-4/MUC4。Anti-Mucin-4/MUC4 Antibody (8K130) 可用于 WB,IHC,FCM。

Anti-Mucin-4/MUC4 Antibody (8K130)

Anti-Mucin-4/MUC4 Antibody (8K130)

Rating icon 还可以
Anti-Mucin-4/MUC4 Antibody (8K130)
产品编号 TMAC-02683 别名 Testis mucin, Pancreatic adenocarcinoma mucin, Mucin-4, MUC-4, Muc4, Ascites sialoglycoprotein (ASGP)

Anti-Mucin-4/MUC4 Antibody (8K130) 是一种 Rabbit 抗体,靶向 Mucin-4/MUC4。Anti-Mucin-4/MUC4 Antibody (8K130) 可用于 WB,IHC,FCM。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-Mucin-4/MUC4 Antibody (8K130) is a Rabbit antibody targeting Mucin-4/MUC4. Anti-Mucin-4/MUC4 Antibody (8K130) can be used in WB,IHC,FCM.
别名Testis mucin, Pancreatic adenocarcinoma mucin, Mucin-4, MUC-4, Muc4, Ascites sialoglycoprotein (ASGP)
Ig Type
IgG
交叉反应
Human,Rat
应用
推荐剂量
WB: 1:500; IHC: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Mucins are a group of high molecular weight glycoproteins consisting of a mucin core protein and O-linked carbohydrates. Mucin 4, a membrane-bound mucin, is the human homolog of the rat sialomucin complex (SMC). Mucin 4 protein consists of Mucin 4α, a large amino mucin type subunit, and Mucin 4β, a transmembrane subunit containing three EGF-like domains. The Mucin 4 gene is the predominant mucin gene expressed in the normal urothelium and is also expressed in several normal tissues such as trachea, lung and testis. Dysregulation of Mucin 4 results in high levels of expression in pancreatic tumors and tumor cell lines. Induction of Mucin 4 in pancreatic carcinoma by all-trans-retinoic acid is mediated through the retinoic acid receptor-α signaling pathway. TGFβ2 serves as an interim mediator of this regulated expression. Alternative splicing in the 3'-end of the Mucin 4 gene generates at least 12 splice variants, which are characterized as two distinct types, a secreted type and a membrane-associated type. Mucin 4 protein acts as a heterodimeric bifunctional cell-surface glycoprotein and forms thick mucous effusion in the diseased middle ear.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 120 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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