Name: Loperamide
Brand: TargetMol
SKU: T206056
Rating: 4.5 (1 reviews)

生物活性

产品描述	Loperamide is a opioid-receptor selective agonist. Its chemical structure is similar to that of haloperidol and pethidine, and it is suitable for acute diarrhea as well as chronic diarrhea caused by various etiology.
靶点活性	κ opioid receptor:156 nM (Ki), δ opioid receptor:48 nM (Ki), μ opioid receptor:3 nM (Ki)
体外活性	方法：Loperamide（0，20，40，60，80，100 µM，24小时）处理 5637、T24和SV-HUC1细胞，CCk8测定细胞活力。结果：Loperamide呈剂量依赖性地降低5637和T24细胞的细胞活力。在SV-HUC1细胞中，当Loperamide浓度高于80 μM时，细胞活力才受到明显抑制。[1]
别名	洛哌丁胺, ADL21294, ADL 2-1294, ADL 21294

化学信息

分子量	477.05
分子式	C₂₉H₃₃ClN₂O₂
CAS No.	53179-11-6
Smiles	CN(C)C(=O)C(CCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1

储存&溶解度

存储	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year Shipping with blue ice. 实际储存温度请以COA为准

Loperamide