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Anti-ADAM15 Antibody-APC (5M69)
还可以产品编号 TMAY-00936A
Anti-ADAM15 Antibody-APC (5M69) 是一种 APC-conjugated Mouse 抗体，靶向 ADAM15。Anti-ADAM15 Antibody-APC (5M69) 可用于 FCM。
Anti-ADAM15 Antibody-APC (5M69)
Anti-ADAM15 Antibody-APC (5M69)
还可以产品编号 TMAY-00936A
Anti-ADAM15 Antibody-APC (5M69) 是一种 APC-conjugated Mouse 抗体，靶向 ADAM15。Anti-ADAM15 Antibody-APC (5M69) 可用于 FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-ADAM15 Antibody-APC (5M69) is a APC-conjugated Mouse antibody targeting ADAM15. Anti-ADAM15 Antibody-APC (5M69) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 5M69 |
| 交叉反应 | Human |
| 验证活性 | Profile of anti-ADAM15 reactivity on MCF-7 cells analyzed by flow cytometry. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ADAM15 (rh ADAM15; TMPY-00961; NP_997074.1; Met1-Thr696) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | ADAM15, also known as Metargidin, is a type I transmembrane glycoprotein belonging to the ADAM (A Disintegrin and Metalloprotease Domain) family of proteins and is widely expressed in different tissues and cell types. Members of this family contain an amino-terminal metalloprotease domain followed by a disintegrin domain, a cysteine-rich region and a membrane proximal EGF-like domain. The disintegrin domain of ADAM15/metargidin contains an RGD tripeptide sequence, suggesting that it may potentially interact with the integrin family of proteins. ADAM15 is a transmembrane multi-domain proteins implicated in proteolysis, cell-cell and cell-matrix interactions in various disease conditions. There is also evidence supporting a role for ADAM15 in angiogenesis and angioinvasion of tumor cells, which are critical for unrestrained tumor growth and metastatic spread. Given its diverse functions, ADAM15 may represent a pivotal regulatory component of tumor progression, an important target for therapeutic intervention, or emerge as a biomarker of disease progression. |
| 偶联 | APC |
| 其他可选修饰符 | Unconjugated/FITC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human ADAM15 protein (TMPY-00961) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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