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Anti-IGFBP-7 Antibody (1G540)

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Anti-IGFBP-7 Antibody (1G540)
产品编号 TMAY-02481
别名 Mac25, insulin-like growth factor binding protein 7, Fstl2, AGM

Anti-IGFBP-7 Antibody (1G540) 是一种 Rabbit 抗体,靶向 IGFBP-7。Anti-IGFBP-7 Antibody (1G540) 可用于 ELISA,ICC/IF。

Anti-IGFBP-7 Antibody (1G540)
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Anti-IGFBP-7 Antibody (1G540)

Rating icon 还可以
Anti-IGFBP-7 Antibody (1G540)
产品编号 TMAY-02481 别名 Mac25, insulin-like growth factor binding protein 7, Fstl2, AGM

Anti-IGFBP-7 Antibody (1G540) 是一种 Rabbit 抗体,靶向 IGFBP-7。Anti-IGFBP-7 Antibody (1G540) 可用于 ELISA,ICC/IF。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-IGFBP-7 Antibody (1G540) is a Rabbit antibody targeting IGFBP-7. Anti-IGFBP-7 Antibody (1G540) can be used in ELISA,ICC/IF.
别名Mac25, insulin-like growth factor binding protein 7, Fstl2, AGM
Ig Type
Rabbit IgG
克隆号
1G540
交叉反应
Human
验证活性
Immunofluorescence staining of IGFBP7 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti-Human IGFBP7 monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue).Positive staining was localized to Cytoplasm.
应用
ELISA,ICC/IF
推荐剂量
ELISA: 1:5000-1:10000; ICC-IF: 1:20-1:100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human IGFBP7 (rh IGFBP7; TMPY-02296; Q16270; Met1-Leu282).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Insulin-like growth factor-binding protein 7 (IGFBP7) is a member of the IGFBP family. It has been identified in colorectal adenocarcinoma (CRC) cell lines. The Insulin-like growth factor-binding protein also known as IGFBP serves as a carrier protein for Insulin-like growth factor 1. IGFBPs are distinct but are sharing regions with strong homology. All members of the IGFBP family bind IGF-I and IGF-II with about equal affinity. Insulin-like growth factor (IGF) binding proteins (IGFBPs) have been shown to either inhibit or enhance the action of IGF or act in an IGF-independent manner in the prostate. IGFBP7 could inhibit cell growth, decrease soft agar colony formation activity, and induce apoptosis in RKO and SW620 cells. There is mounting evidence that the structure of the IGFBP proteins plays a key role in the regulation of IGF bioavailability, by modulating its molecular size, capillary membrane permeability, target tissue specificity, cell membrane adherence, and IGF affinity.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human IGFBP7 protein (TMPY-02296)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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