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Anti-IGFBP-7 Antibody (1G540)
还可以产品编号 TMAY-02481
Anti-IGFBP-7 Antibody (1G540) 是一种 Rabbit 抗体，靶向 IGFBP-7。Anti-IGFBP-7 Antibody (1G540) 可用于 ELISA,ICC/IF。
Anti-IGFBP-7 Antibody (1G540)
Anti-IGFBP-7 Antibody (1G540)
还可以产品编号 TMAY-02481
Anti-IGFBP-7 Antibody (1G540) 是一种 Rabbit 抗体，靶向 IGFBP-7。Anti-IGFBP-7 Antibody (1G540) 可用于 ELISA,ICC/IF。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-IGFBP-7 Antibody (1G540) is a Rabbit antibody targeting IGFBP-7. Anti-IGFBP-7 Antibody (1G540) can be used in ELISA,ICC/IF. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 1G540 |
| 交叉反应 | Human |
| 验证活性 | Immunofluorescence staining of IGFBP7 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti-Human IGFBP7 monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue).Positive staining was localized to Cytoplasm. |
| 应用 | ELISA,ICC/IF |
| 推荐剂量 | ELISA: 1:5000-1:10000; ICC-IF: 1:20-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human IGFBP7 (rh IGFBP7; TMPY-02296; Q16270; Met1-Leu282). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Insulin-like growth factor-binding protein 7 (IGFBP7) is a member of the IGFBP family. It has been identified in colorectal adenocarcinoma (CRC) cell lines. The Insulin-like growth factor-binding protein also known as IGFBP serves as a carrier protein for Insulin-like growth factor 1. IGFBPs are distinct but are sharing regions with strong homology. All members of the IGFBP family bind IGF-I and IGF-II with about equal affinity. Insulin-like growth factor (IGF) binding proteins (IGFBPs) have been shown to either inhibit or enhance the action of IGF or act in an IGF-independent manner in the prostate. IGFBP7 could inhibit cell growth, decrease soft agar colony formation activity, and induce apoptosis in RKO and SW620 cells. There is mounting evidence that the structure of the IGFBP proteins plays a key role in the regulation of IGF bioavailability, by modulating its molecular size, capillary membrane permeability, target tissue specificity, cell membrane adherence, and IGF affinity. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human IGFBP7 protein (TMPY-02296) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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