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Anti-PIGR Antibody (5O982)

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Anti-PIGR Antibody (5O982)
产品编号 TMAY-00318
别名 polymeric immunoglobulin receptor, Pigr

Anti-PIGR Antibody (5O982) 是一种 Rabbit 抗体,靶向 PIGR。Anti-PIGR Antibody (5O982) 可用于 IHC-P,ICC/IF。

Anti-PIGR Antibody (5O982)

Anti-PIGR Antibody (5O982)

Rating icon 还可以
Anti-PIGR Antibody (5O982)
产品编号 TMAY-00318 别名 polymeric immunoglobulin receptor, Pigr

Anti-PIGR Antibody (5O982) 是一种 Rabbit 抗体,靶向 PIGR。Anti-PIGR Antibody (5O982) 可用于 IHC-P,ICC/IF。

规格价格库存数量
20 μL
¥ 795
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100 μL
¥ 2,289
5日内发货
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产品介绍

生物活性
产品描述
Anti-PIGR Antibody (5O982) is a Rabbit antibody targeting PIGR. Anti-PIGR Antibody (5O982) can be used in IHC-P,ICC/IF.
别名polymeric immunoglobulin receptor, Pigr
Ig Type
Rabbit IgG
克隆号
5O982
交叉反应
Human
验证活性
1. Immunochemical staining of human PIGR in human liver (cirrhosis) with rabbit monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). Positive staining was localized to hepatocyte.
2. Immunochemical staining of human PIGR in human breast carcinoma with rabbit monoclonal antibody (1:60, formalin-fixed paraffin embedded sections).
3. Immunofluorescence staining of PIGR in HepG2 cells. Cells were fixed with 4% PFA,blocked with 10% serum, and incubated with rabbit anti-Y PIGR monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue).Positive staining was localized to Cytoplasm.
应用
推荐剂量
IHC-P: 1:50-1:200; ICC-IF: 1:20-1:100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human PIGR (rh PIGR; TMPY-00902; NP_002635.2; Met1-Arg638,365Ser/Gly).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Polymeric immunoglobulin receptor, also known as PIGR, is a member of the immunoglobulin superfamily and a Fc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions. PIGR is expressed on several glandular epithelia including those of liver and breast. The deduced amino-acid sequence has a length of 764 residues and shows an overall similarity of 56% and 64% with the rabbit and rat counterpart. PIGR mediates transcellular transport of polymeric immunoglobulin molecules, and thus facilitates the secretion of IgA and IgM. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment of PIGR.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human PIGR protein (TMPY-00902)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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