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Anti-PIGR Antibody (5O982)

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Anti-PIGR Antibody (5O982)
产品编号 TMAY-00318
别名 polymeric immunoglobulin receptor, Pigr

Anti-PIGR Antibody (5O982) 是一种 Rabbit 抗体,靶向 PIGR。Anti-PIGR Antibody (5O982) 可用于 ICC/IF,IHC-P。

Anti-PIGR Antibody (5O982)

Anti-PIGR Antibody (5O982)

Rating icon 还可以
Anti-PIGR Antibody (5O982)
产品编号 TMAY-00318 别名 polymeric immunoglobulin receptor, Pigr

Anti-PIGR Antibody (5O982) 是一种 Rabbit 抗体,靶向 PIGR。Anti-PIGR Antibody (5O982) 可用于 ICC/IF,IHC-P。

规格价格库存数量
20 μL
¥ 795
5日内发货
100 μL
¥ 2,289
5日内发货
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产品介绍

生物活性
产品描述
Anti-PIGR Antibody (5O982) is a Rabbit antibody targeting PIGR. Anti-PIGR Antibody (5O982) can be used in ICC/IF,IHC-P.
别名polymeric immunoglobulin receptor, Pigr
Ig Type
Rabbit IgG
克隆号
5O982
交叉反应
Human
特异性
Human pIgR
验证活性
1. Immunochemical staining of human PIGR in human liver (cirrhosis) with rabbit monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). Positive staining was localized to hepatocyte.
2. Immunochemical staining of human PIGR in human breast carcinoma with rabbit monoclonal antibody (1:60, formalin-fixed paraffin embedded sections).
3. Immunofluorescence staining of PIGR in HepG2 cells. Cells were fixed with 4% PFA,blocked with 10% serum, and incubated with rabbit anti-Y PIGR monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue).Positive staining was localized to Cytoplasm.
应用
推荐剂量
IHC-P: 1:50-1:200; ICC-IF: 1:20-1:100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human PIGR (rh PIGR; TMPY-00902; NP_002635.2; Met1-Arg638,365Ser/Gly).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Polymeric immunoglobulin receptor, also known as PIGR, is a member of the immunoglobulin superfamily and a Fc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions. PIGR is expressed on several glandular epithelia including those of liver and breast. The deduced amino-acid sequence has a length of 764 residues and shows an overall similarity of 56% and 64% with the rabbit and rat counterpart. PIGR mediates transcellular transport of polymeric immunoglobulin molecules, and thus facilitates the secretion of IgA and IgM. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment of PIGR.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human PIGR protein (TMPY-00902)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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