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Anti-PIGR Antibody (5O982)
还可以产品编号 TMAY-00318
Anti-PIGR Antibody (5O982) 是一种 Rabbit 抗体，靶向 PIGR。Anti-PIGR Antibody (5O982) 可用于 IHC-P,ICC/IF。
Anti-PIGR Antibody (5O982)
Anti-PIGR Antibody (5O982)
还可以产品编号 TMAY-00318
Anti-PIGR Antibody (5O982) 是一种 Rabbit 抗体，靶向 PIGR。Anti-PIGR Antibody (5O982) 可用于 IHC-P,ICC/IF。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-PIGR Antibody (5O982) is a Rabbit antibody targeting PIGR. Anti-PIGR Antibody (5O982) can be used in IHC-P,ICC/IF. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 5O982 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human PIGR in human liver (cirrhosis) with rabbit monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). Positive staining was localized to hepatocyte. 2. Immunochemical staining of human PIGR in human breast carcinoma with rabbit monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). 3. Immunofluorescence staining of PIGR in HepG2 cells. Cells were fixed with 4% PFA,blocked with 10% serum, and incubated with rabbit anti-Y PIGR monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue).Positive staining was localized to Cytoplasm. |
| 应用 | IHC-P,ICC/IF |
| 推荐剂量 | IHC-P: 1:50-1:200; ICC-IF: 1:20-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human PIGR (rh PIGR; TMPY-00902; NP_002635.2; Met1-Arg638,365Ser/Gly). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Polymeric immunoglobulin receptor, also known as PIGR, is a member of the immunoglobulin superfamily and a Fc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions. PIGR is expressed on several glandular epithelia including those of liver and breast. The deduced amino-acid sequence has a length of 764 residues and shows an overall similarity of 56% and 64% with the rabbit and rat counterpart. PIGR mediates transcellular transport of polymeric immunoglobulin molecules, and thus facilitates the secretion of IgA and IgM. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment of PIGR. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human PIGR protein (TMPY-00902) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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