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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ELF4 Polyclonal Antibody

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货号 TMAB-05535

Anti-ELF4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ELF4。Anti-ELF4 Polyclonal Antibody 可用于 FCM。

Anti-ELF4 Polyclonal Antibody

Anti-ELF4 Polyclonal Antibody

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货号 TMAB-05535

Anti-ELF4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ELF4。Anti-ELF4 Polyclonal Antibody 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-ELF4 Polyclonal Antibody is a Rabbit antibody targeting ELF4. Anti-ELF4 Polyclonal Antibody can be used in FCM.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Sheep)
应用FCM
推荐剂量
FCM: 3μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus > PML body. Accumulation into PML nuclear bodies is mediated by PML.
组织特异性Abundantly expressed in the placenta and in a variety of myeloid leukemia cell lines. Moderate levels of expression in heart, lung, spleen, thymus, peripheral blood lymphocytes, ovary and colon. Lower levels of expression in Jurkat T-cells and other T-cell lines and no expression in brain.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a transcriptional activator that binds and activates the promoters of the CSF2, IL3, IL8, and PRF1 genes. The encoded protein is involved in natural killer cell development and function, innate immunity, and induction of cell cycle arrest in naive CD8+ cells. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Jan 2010]
抗原信息
免疫原
KLH conjugated synthetic peptide: human ELF4
抗原种属
Human
基因名称
ELF4
基因ID
2000
蛋白名称
ETS-related transcription factor Elf-4
Uniprot ID
Q99607
功能
Transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. Acts synergistically with RUNX1 to transactivate the IL3 promoter (By similarity). Also transactivates the PRF1 promoter in natural killer (NK) cells. Plays a role in the development and function of NK and NK T-cells and in innate immunity. Controls the proliferation and homing of CD8+ T cells via the Kruppel-like factors KLF4 and KLF2 (By similarity). Controls cell senescence in a p53-dependent manner. Can also promote celular transformation through inhibition of the p16 pathway.
化学信息
分子量Theoretical: 71 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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