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CD27/TNFRSF7 Protein, Human, Recombinant (His)

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产品编号 TMPY-03401

CD27/TNFRSF7 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 20.77 kDa and the accession number is P26842.

CD27/TNFRSF7 Protein, Human, Recombinant (His)

一键复制产品信息

产品编号 TMPY-03401

CD27/TNFRSF7 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 20.77 kDa and the accession number is P26842.

规格	价格	库存
5 μg	¥ 429	6-8日内发货
10 μg	¥ 697	6-8日内发货
20 μg	¥ 1,150	5日内发货
50 μg	¥ 2,260	5日内发货
100 μg	¥ 3,820	In stock
200 μg	¥ 6,390	5日内发货
500 μg	¥ 12,580	5日内发货

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产品信息

生物活性	Measured by its binding ability in a functional ELISA. Immobilized human CD27-his at 10 μg/mL (100 μl/well) can bind biotinylated human CD70-Fc , The EC50 of biotinylated human CD70-Fc is 57-85 ng/mL.
产品描述	CD27/TNFRSF7 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 20.77 kDa and the accession number is P26842.
种属	Human
表达系统	Baculovirus Insect Cells
标签	C-His
蛋白编号	P26842
别名	Tp55,TNFRSF7,T14,S152.LPFS2,S152. LPFS2,S152,CD27 molecule
蛋白构建	A DNA sequence encoding the human CD27(P26842) ( Met 1-Ile192) was expressed with a C-terminal polyhistidine tag. Predicted N terminal: Ala 20
蛋白纯度	> 85 % as determined by SDS-PAGE
分子量	20.77 kDa (predicted); 27 kDa (reducing condition, due to glycosylation)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 500 mM NaCl, 10% glycerol, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a type I transmembrane glycoprotein of about 55 kDa existing as disulfide-linked homodimer, CD27 has been shown to play roles in lymphoid proliferation, differentiation, and apoptosis.It has an important role in the generation of T cell immunity and is an robust marker for normal memory B cells. It is a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD70 on lymphocytes and dendritic cells. The CD27-CD70 interaction is required for Th1 generation responses to differentiation signals and long-term maintenance of T cell immunity, and meanwhile, plays a key role in regulating B-cell differentiation, activation and immunoglobulin synthesis.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy