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Anti-Caspase-14 Antibody (1S873)
还可以产品编号 TMAY-02108
Anti-Caspase-14 Antibody (1S873) 是一种 Mouse 抗体，靶向 Caspase-14。Anti-Caspase-14 Antibody (1S873) 可用于 ELISA。
Anti-Caspase-14 Antibody (1S873)
Anti-Caspase-14 Antibody (1S873)
还可以产品编号 TMAY-02108
Anti-Caspase-14 Antibody (1S873) 是一种 Mouse 抗体，靶向 Caspase-14。Anti-Caspase-14 Antibody (1S873) 可用于 ELISA。
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抗原信息
| 产品描述 | Anti-Caspase-14 Antibody (1S873) is a Mouse antibody targeting Caspase-14. Anti-Caspase-14 Antibody (1S873) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG2b |
| 克隆号 | 1S873 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Caspase-14 / CASP14 (rh Caspase-14 / CASP14; TMPY-01824; NP_036246.1; Ser 2-Gln 242). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Caspase 14 is a member of the caspase family. Caspases are a kind of cysteine proteinase consisting of a prodomain plus large and small catalytic subunits, that play a central role in cell apoptosis. Caspase 14 possesses an unusually short prodomain and is highly expressed in embryonic tissues but absent from most of the adult tissues except for the skin, which suggests a role in ontogenesis and skin physiology. Unlike the other short prodomain caspases(caspase-3, caspase-6, and caspase-7), Caspase 14 was not processed by multiple death stimuli including activation of members of the tumor necrosis factor receptor family and expression of proapaptotic members of the bcl-2 family. Caspase 14 has been described to be processed and activated by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may take part in keratinocyte terminal differentiation, which is essential for the skin barrier. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Caspase-14 / CASP14 protein (TMPY-01824) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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