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Anti-BMPRIB Antibody (5K774)
还可以产品编号 TMAY-00856
Anti-BMPRIB Antibody (5K774) 是一种 Mouse 抗体，靶向 BMPRIB。Anti-BMPRIB Antibody (5K774) 可用于 ELISA。
Anti-BMPRIB Antibody (5K774)
Anti-BMPRIB Antibody (5K774)
还可以产品编号 TMAY-00856
Anti-BMPRIB Antibody (5K774) 是一种 Mouse 抗体，靶向 BMPRIB。Anti-BMPRIB Antibody (5K774) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-BMPRIB Antibody (5K774) is a Mouse antibody targeting BMPRIB. Anti-BMPRIB Antibody (5K774) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 5K774 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ALK-6 / BMPR1B (rh ALK-6 / BMPR1B; TMPY-04367; NP_001194.1; Arg149-Leu502). The IgG fraction of the cell culture supernatant was purified by Protein A affinity. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | BMPR1B(bone morphogenetic protein receptor, type IB), also known as ALK6, is a member of the bone morphogenetic protein (BMP) receptor family. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. BMPR1B is the major transducer of signals in precartilaginous condensations as demonstrated in experiments using constitutively active BMPR1B receptors. BMPR1B is a more effective transducer of GDF5 than BMPR1A. Unlike BMPR1A null mice, which die at an early embryonic stage, BMPR1B null mice are viable. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human ALK-6 / BMPR1B protein (TMPY-04367) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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