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LAIR2 Protein, Human, Recombinant,Low Endotoxin

产品编号 TMPY-02320

别名: LAIR2, leukocyte associated immunoglobulin like receptor 2, XXbac-BCX535A19.6, MGC71634, CD306

LAIR2 Protein, Human, Recombinant,Low Endotoxin is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.1 kDa and the accession number is Q6ISS4-1.

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LAIR2 Protein, Human, Recombinant,Low Endotoxin

规格	价格/CNY		货期	数量
5 μg	￥ 1,350		5日内发货
10 μg	￥ 2,270		5日内发货

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生物活性	Testing in progress
产品描述	LAIR2 Protein, Human, Recombinant,Low Endotoxin is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.1 kDa and the accession number is Q6ISS4-1.

种属	Human
表达系统	HEK293 Cells
标签	Tag Free
蛋白编号	Q6ISS4-1
别名	LAIR2, leukocyte associated immunoglobulin like receptor 2, XXbac-BCX535A19.6, MGC71634, CD306
蛋白构建	The Human LAIR2 (NP_002279.2) (Met 1-Pro 152) was expressed and purified.
蛋白纯度	> 94 % as determined by SDS-PAGE
分子量	14.1 kDa (predicted)

内毒素	< 0.005 EU/μg of the protein as determined by the LAL method
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	Leukocyte-associated immunoglobulin-like receptor 2 ( LAIR2 ), also known as CD306, is a 131 amino acid protein containing one Ig-like C2-type domain. It is expressed as a soluble receptor exhibiting high affinity for various collagen molecules to which it binds in a hydroxyproline-dependent manner. LAIR2 is a member of the immunoglobulin superfamily and was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. LAIR2 is thought to be secreted and may help modulate mucosal tolerance. As a natural competitor for LAIR1, soluble LAIR2 prevents binding of human LAIR1 to collagens and LAIR1 cross-linking, thereby regulating its inhibitory potential. Accordingly, LAIR2 is suggested to perform an immunoregulatory function.

参考文献

1. Meyaard, L. et al.,1997, Immunity.7:283-290. 2. Meyaard, L. et al.,1999, J. Immunol. 162:5800-5804. 3. Meyaard, L. et al., 2001, J. Exp. Med. 194 (1): 107-112. 4. Meyaard, L., 2003, J Biol Regul Homeost Agents. 17 (4): 330-333. 5. Lebbink, R. J. et al., 2008, J Immunol. 180 (3):1662-1669. 6. Lebbink,R.J. et al., 2009, Matrix Biol. 28 (4):202-210.

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Keywords

LAIR2 Protein, Human, Recombinant,Low Endotoxin LAIR2 CD 306 leukocyte associated immunoglobulin like receptor 2 MGC 71634 XXbac-BCX535A19.6 MGC71634 MGC-71634 LAIR 2 CD-306 CD306 LAIR-2 recombinant recombinant-proteins proteins protein

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